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Synthesis of new heterocyclic systems—substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines]

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Abstract

Methods have been developed for the synthesis of new heterocyclic systems, spiro[chromene-4,3′- indoles] and spiro[indole-3,4′-quinolines] by the base-catalyzed domino reaction of isatins with 5,5-dimethylcyclohexane- 1,3-dione (or 5,5-dimethyl-3-anilinocyclohex-2-en-1-one) and ethyl cyanoacetate.

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Authors and Affiliations

  1. Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, Yerevan, 0014, Armenia

    S. A. Pogosyan, Dzh. A. Avakimyan & H. M. Stepanyan

Authors
  1. S. A. Pogosyan
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  2. Dzh. A. Avakimyan
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  3. H. M. Stepanyan
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Correspondence to S. A. Pogosyan.

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Original Russian Text © S.A. Pogosyan, Dzh.A. Avakimyan, H.M. Stepanyan, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 9, pp. 1320–1323.

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Pogosyan, S.A., Avakimyan, D.A. & Stepanyan, H.M. Synthesis of new heterocyclic systems—substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines]. Russ J Org Chem 52, 1308–1311 (2016). https://doi.org/10.1134/S1070428016090098

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  • DOI: https://doi.org/10.1134/S1070428016090098

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