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Synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde and its transformation into amino alcohols containing an indan-1,3-dione fragment

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Abstract

A procedure for the synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde was developed and optimized. Its reaction with indan-1,3-dione, followed by treatment with amines, afforded 1,2-amino alcohols containing an indole fragment.

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Correspondence to L. D. Popov.

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Original Russian Text © L.D. Popov, K.F. Suzdalev, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 6, pp. 858–861.

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Popov, L.D., Suzdalev, K.F. Synthesis of 1-(oxiran-2-ylmethyl)-1H-indole-3-carbaldehyde and its transformation into amino alcohols containing an indan-1,3-dione fragment. Russ J Org Chem 52, 844–847 (2016). https://doi.org/10.1134/S1070428016060142

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  • DOI: https://doi.org/10.1134/S1070428016060142

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