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Russian Journal of Organic Chemistry

, Volume 52, Issue 5, pp 655–660 | Cite as

Synthesis of 1-substituted 5-alkyl(aryl)-1,3-dihydro-2H-pyrrol-2-ones. Azocoupling with diazonium salts

  • V. S. Grinev
  • O. A. Amal’chieva
  • A. Yu. Egorova
Article

Abstract

Reactions of 5-alkyl- and 5-aryl-3H-furan-2-ones with 1,3- and 1,4-binucleophiles of aromatic series were carried out for the first time under various conditions. In the presence of a base the reaction resulted in 1-R-1,3-dihydro-2Н-pyrrol-2-ones, under milder conditions intermediates were isolated, 4-aryl-4-oxobutanamides. The structure of the latter was proved by spectral methods. By an example of 1-R-1,3-dihydro-2Н-pyrrol-2-ones the possibility was demonstrated of their functionalization via introducing an aryldiazenyl fragment.

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • V. S. Grinev
    • 1
    • 2
  • O. A. Amal’chieva
    • 2
  • A. Yu. Egorova
    • 2
  1. 1.Institute of Biochemistry and Physiology of Plants and MicroorganismsRussian Academy of SciencesSaratovRussia
  2. 2.Chernyshevskii Saratov State National Research UniversitySaratovRussia

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