Abstract
Fused tricyclic aziridines, methyl rel-(2R,2aR,3R,4R,4aR,4bS)- and rel-(2S,2aR,3R,4R,4aR,4bS)-4-hydroxy-2,4a-dimethoxyhexahydro-1-oxa-2b-azacyclopropa[cd]pentalene-3-carboxylates, have been synthesized as possible precursors to β-lactams. The product structure has been determined by two-dimensional NMR techniques in combination with computational methods.
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Original Russian Text © Z.R. Valiullina, A.N. Lobov, N.K. Selezneva, M.S. Miftakhov, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 3, pp. 370–375.
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Valiullina, Z.R., Lobov, A.N., Selezneva, N.K. et al. Pyrrolidine synthons for β-lactams. Russ J Org Chem 52, 349–354 (2016). https://doi.org/10.1134/S1070428016030106
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DOI: https://doi.org/10.1134/S1070428016030106