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Aspartic acid as a highly efficient and nontoxic organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions

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Abstract

Aspartic acid was found to be an efficient organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions. The remarkable advantages offered by this method are the inexpensive and green catalyst, mild reaction conditions, simple procedures, and excellent yield of products.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Ilam University, P.O. Box 69315516, Ilam, Iran

    A. Ghorbani-Choghamarani, M. Hajjami, F. Gholamian & G. Azadi

Authors
  1. A. Ghorbani-Choghamarani
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  2. M. Hajjami
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  3. F. Gholamian
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  4. G. Azadi
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Correspondence to A. Ghorbani-Choghamarani.

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Ghorbani-Choghamarani, A., Hajjami, M., Gholamian, F. et al. Aspartic acid as a highly efficient and nontoxic organocatalyst for the one-pot synthesis of tri- and tetrasubstituted imidazoles under solvent-free conditions. Russ J Org Chem 51, 352–356 (2015). https://doi.org/10.1134/S1070428015030100

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