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Synthesis, molecular and crystal structure of new 9,10-substituted deazaflavins

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Abstract

Cyclocondensation of 6-N-(3-hydroxypropyl)aminouracyl with 2-fluoro- or 2,3-dimethoxy-substituted benzaldehydes provided the corresponding 9,10-substituted 5-deazaflavins {pyrimido[4,5-b]quinoline-2,4-(3H,10H)diones}. X-ray diffraction analysis was carried out for 9-methoxy-10-(3-hydroxy-propyl)-substituted 5-deazaflavin derivative.

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Authors and Affiliations

  1. A.L. Mndzhoyan Institute of Fine Organic Chemistry, R&D Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenian Republic, pr. Azatutyan 26, Yerevan, 0014, Armenia

    R. G. Melik-Ohandzanyan, T. R. Hovsepyan & S. G. Israelyan

  2. Center of Molecular Structures Studies, R&D Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenian Republic, Yerevan, Armenia

    R. A. Tamazyan, A. G. Ayvazyan & G. A. Panosyan

Authors
  1. R. G. Melik-Ohandzanyan
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  2. T. R. Hovsepyan
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  3. S. G. Israelyan
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  4. R. A. Tamazyan
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  5. A. G. Ayvazyan
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  6. G. A. Panosyan
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Corresponding author

Correspondence to R. G. Melik-Ohandzanyan.

Additional information

Original Russian Text © R.G. Melik-Ohandzanyan, T.R. Hovsepyan, S.G. Israelyan, R.A. Tamazyan, A.G. Ayvazyan, G.A. Panosyan, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 8, pp. 1178–1180.

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Melik-Ohandzanyan, R.G., Hovsepyan, T.R., Israelyan, S.G. et al. Synthesis, molecular and crystal structure of new 9,10-substituted deazaflavins. Russ J Org Chem 50, 1161–1163 (2014). https://doi.org/10.1134/S1070428014080156

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  • DOI: https://doi.org/10.1134/S1070428014080156

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