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First synthesis of steroidal 1,2,4-trioxolanes

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Abstract

Griesbaum ozonolysis of mixtures of methyl 3-(methoxyimino)-5β-cholan-24-oate with ketones (cyclohexanone, methyl trifluoromethyl ketone, and phenyl trifluoromethyl ketone) afforded for the first time steroidal 1,2,4-trioxolanes which were isolated as mixtures of stereoisomers.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Research Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Bashkortostan, Russia

    E. Yu. Yamansarov, O. B. Kazakova, N. I. Medvedeva, D. V. Kazakov, O. S. Kukovinets & G. A. Tolstikov

Authors
  1. E. Yu. Yamansarov
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  2. O. B. Kazakova
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  3. N. I. Medvedeva
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  4. D. V. Kazakov
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  5. O. S. Kukovinets
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  6. G. A. Tolstikov
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Corresponding author

Correspondence to O. B. Kazakova.

Additional information

Original Russian Text © E.Yu. Yamansarov, O.B. Kazakova, N.I. Medvedeva, D.V. Kazakov, O.S. Kukovinets, G.A. Tolstikov, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 7, pp. 1059–1062.

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Yamansarov, E.Y., Kazakova, O.B., Medvedeva, N.I. et al. First synthesis of steroidal 1,2,4-trioxolanes. Russ J Org Chem 50, 1043–1047 (2014). https://doi.org/10.1134/S1070428014070197

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  • DOI: https://doi.org/10.1134/S1070428014070197

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