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Synthesis of 12-hetaryl-9,9-dimethyl-7,8,9,10-tetrahydrobenzo[a]acridin-11(12H)-ones

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Abstract

Three-component condensation of naphthalen-2-amine with 5-arylfuran(thiophene, N-methylpyrrole)-2-carbaldehyde and 5,5-dimethylcyclohexane-1,3-dione, as well as condensation of N-[(5-arylfuran(thiophen)-2-ylmethylidene]naphthalen-2-amine with 5,5-dimethylcyclohexane-1,3-dione gave the corresponding 12-[5-arylfuran(thiophen, N-methylpyrrol)-2-yl]-7,8,9,10-tetradrobenzo[a]acridin-11(12H)-ones.

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Authors and Affiliations

  1. Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072, Belarus

    N. G. Kozlov, Yu. D. Zhikharko, E. D. Skakovskii & L. I. Basalaeva

  2. Ivan Franko National University of Lviv, Universytetska ul. 1, Lviv, 79000, Ukraine

    R. Z. Lytvyn, Yu. I. Gorak & M. D. Obushak

  3. Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, ul. Akademika Kuprevicha 5/2, Minsk, 220141, Belarus

    A. V. Baranovskii

Authors
  1. N. G. Kozlov
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  2. Yu. D. Zhikharko
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  3. R. Z. Lytvyn
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  4. Yu. I. Gorak
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  5. E. D. Skakovskii
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  6. A. V. Baranovskii
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  7. L. I. Basalaeva
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  8. M. D. Obushak
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Corresponding author

Correspondence to N. G. Kozlov.

Additional information

Original Russian Text © N.G. Kozlov, Yu.D. Zhikharko, R.Z. Lytvyn, Yu.I. Gorak, E.D. Skakovskii, A.V. Baranovskii, L.I. Basalaeva, M.D. Obushak, 2014, published in Zhurnal Organicheskoi Khimii, 2014, Vol. 50, No. 6, pp. 850–856.

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Kozlov, N.G., Zhikharko, Y.D., Lytvyn, R.Z. et al. Synthesis of 12-hetaryl-9,9-dimethyl-7,8,9,10-tetrahydrobenzo[a]acridin-11(12H)-ones. Russ J Org Chem 50, 833–839 (2014). https://doi.org/10.1134/S107042801406013X

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  • DOI: https://doi.org/10.1134/S107042801406013X

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