Abstract
A new disaccharide block for OSW-1 natural steroidal antitumor agent was described. Regioisomeric 2- and 3-O-p-methoxybenzoyl derivatives of phenyl 1-thio-β-d-xylopyranoside and phenyl 2-O-acetyl-1-thio-β-l-arabinopyranoside derivatives blocked at positions 3 and 4 by R3Si groups were synthesized with a view to use them in the preparation of OSW-1 analogs modified at the disaccharide fragment.
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Original Russian Text © L.S. Khasanova, F.A. Gimalova, Z.R. Valiullina, N.K. Selezneva, R.M. Ganieva, L.V. Spirikhin, M.S. Miftakhov, 2012, published in Zhurnal Organicheskoi Khimii, 2012, Vol. 48, No. 9, pp. 1239–1245.
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Khasanova, L.S., Gimalova, F.A., Valiullina, Z.R. et al. New disaccharide blocks for OSW-1 and its analogs. Russ J Org Chem 48, 1238–1244 (2012). https://doi.org/10.1134/S1070428012090163
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DOI: https://doi.org/10.1134/S1070428012090163