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Design, synthesis, and properties of neoglycolipids based on ethylene glycoles conjugated with lactose as components of targeted delivery systems of biologically active compounds

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Abstract

Synthesis has been developed of a series of new aliphatic lactose derivatives as components of liposomal targeted delivery systems distinguished by the length and the number of aliphatic chains and also by the length of the spacer fragment. The structure of compounds synthesized has been established by means of 1H NMR spectroscopy.

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Authors and Affiliations

  1. Lomonosov Moscow State University of Fine Chemical Technologies, Moscow, 119571, Russia

    L. Yu. Gur’eva, A. K. Bol’sheborodova & Yu. L. Sebyakin

Authors
  1. L. Yu. Gur’eva
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  2. A. K. Bol’sheborodova
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  3. Yu. L. Sebyakin
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Correspondence to L. Yu. Gur’eva.

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Original English Text © L.Yu. Gur’eva, A.K. Bol’sheborodova, Yu.L. Sebyakin, 2012, published in Zhurnal Organicheskoi Khimii, 2012, Vol. 48, No. 8, pp. 1051–1058.

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Gur’eva, L.Y., Bol’sheborodova, A.K. & Sebyakin, Y.L. Design, synthesis, and properties of neoglycolipids based on ethylene glycoles conjugated with lactose as components of targeted delivery systems of biologically active compounds. Russ J Org Chem 48, 1047–1054 (2012). https://doi.org/10.1134/S1070428012080039

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  • DOI: https://doi.org/10.1134/S1070428012080039

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