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Russian Journal of Organic Chemistry

, Volume 47, Issue 11, pp 1727–1732 | Cite as

Heterocyclizations of functionalized heterocumulenes with C,N-, C,O-, and C,S-binucleophiles: XIII. Synthesis of dialkyl 2-oxo-3-allyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylates and their reaction with arylhydroxymoyl chlorides

  • O. V. Kushnir
  • N. V. Mel’nichenko
  • M. V. Vovk
Article

Abstract

Dialkyl 2-oxo-3-allyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylates obtained by condensation of 1-chlorobenzyl isocyanates with N-allylfumarates reacted regioselectively with arylhydroxymoyl chlorides with the formation of dialkyl 6-aryl-3-[(3-aryl-4,5-dihydro-5-isoxazolyl)methyl]-2-oxo-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylates.

Keywords

Dicarboxylate Anhydrous Toluene Isoxazoline Nitrile Oxide Ammonium Chloride Solution 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • O. V. Kushnir
    • 1
  • N. V. Mel’nichenko
    • 2
  • M. V. Vovk
    • 2
  1. 1.Fed’kovich Chernovtsy National UniversityChernovtsyUkraine
  2. 2.Institute of Organic ChemistryNational Academy of Sciences of UkraineKievUkraine

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