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Synthesis of 4,N-diaryl-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamides

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Abstract

Cyclohexane-1,3-dione reacted with substituted benzaldehydes and N-arylacetoacetamides in the presence of ammonium acetate under solvent-free conditions (150–160°C, 10–20 min) to give the corresponding 4,N-diaryl-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamides. The product structure was determined by IR and 1H NMR spectroscopy and mass spectrometry.

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References

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Correspondence to V. L. Gein.

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Original Russian Text © V.L. Gein, M.I. Kazantseva, A.A. Kurbatova, 2011, published in Zhurnal Organicheskoi Khimii, 2011, Vol. 47, No. 6, pp. 870–871.

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Gein, V.L., Kazantseva, M.I. & Kurbatova, A.A. Synthesis of 4,N-diaryl-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamides. Russ J Org Chem 47, 886–888 (2011). https://doi.org/10.1134/S1070428011060091

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  • DOI: https://doi.org/10.1134/S1070428011060091

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