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Synthetic transformations of higher terpenoids: XXIV. Synthesis of cyanoethyl derivatives of lupane triterpenoids and their transformation into 1,2,4-oxadiazoles

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Abstract

Cyanoethylation of lupane triterpenoids was performed. Amide oximes of 3β-O-(2-cyanoethyl)-betulinic acid methyl ester and 3β-O-acetyl-28-O-(2-cyanoethyl)betulin and the corresponding O-[2-(1,2,4-oxadiazol-3-yl)ethyl] lupane derivatives were obtained.

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Authors and Affiliations

  1. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Division, Russian Academy of Sciences, pr. Akademika Lavrent’eva 9, Novosibirsk, 630090, Russia

    A. N. Antimonova, N. V. Uzenkova, N. I. Petrenko, M. M. Shakirov, E. E. Shul’ts & G. A. Tolstikov

Authors
  1. A. N. Antimonova
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  2. N. V. Uzenkova
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  3. N. I. Petrenko
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  4. M. M. Shakirov
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  5. E. E. Shul’ts
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  6. G. A. Tolstikov
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Corresponding author

Correspondence to E. E. Shul’ts.

Additional information

Original Russian Text © A.N. Antimonova, N.V. Uzenkova, N.I. Petrenko, M.M. Shakirov, E.E. Shul’ts, G.A. Tolstikov, 2011, published in Zhurnal Organicheskoi Khimii, 2011, Vol. 47, No. 4, pp. 586–596.

For communication XXIII, see [1].

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Antimonova, A.N., Uzenkova, N.V., Petrenko, N.I. et al. Synthetic transformations of higher terpenoids: XXIV. Synthesis of cyanoethyl derivatives of lupane triterpenoids and their transformation into 1,2,4-oxadiazoles. Russ J Org Chem 47, 589–601 (2011). https://doi.org/10.1134/S1070428011040208

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  • DOI: https://doi.org/10.1134/S1070428011040208

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