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Synthesis of fused 2′-amino-3′-R-spiro-[indole-3,4′-pyran]-2(1H)-ones

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Abstract

An efficient one-pot procedure has been proposed for the synthesis of fused 2′-amino-3′-R-spiro-[indole-3,4′-pyran]-2(1H)-ones via base-catalyzed three-component condensation of isatins with the corresponding nitriles and 1,3-diketones.

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Authors and Affiliations

  1. Natsional Pharmaceutical University, ul. Pushkinskaya 53, Khar’kov, 61002, Ukraine

    L. A. Shemchuk, V. P. Chernykh & R. G. Red’kin

Authors
  1. L. A. Shemchuk
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  2. V. P. Chernykh
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  3. R. G. Red’kin
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Correspondence to R. G. Red’kin.

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Original Russian Text © L.A. Shemchuk, V.P. Chernykh, R.G. Red’kin, 2008, published in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 12, pp. 1816–1821.

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Shemchuk, L.A., Chernykh, V.P. & Red’kin, R.G. Synthesis of fused 2′-amino-3′-R-spiro-[indole-3,4′-pyran]-2(1H)-ones. Russ J Org Chem 44, 1789–1794 (2008). https://doi.org/10.1134/S1070428008120117

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  • DOI: https://doi.org/10.1134/S1070428008120117

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