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A simple and efficient synthesis of 2-aryl-substituted benzimidazoles

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Abstract

Sodium hydrogen sulfite was used to promote condensation of o-phenylenediamine with aromatic aldehydes in dimethylformamide to obtain the corresponding 2-arylbenzimidazoles. The procedure is simple and convenient, and it implies inexpensive promoter and is characterized by short reaction time and easy purification of the final products.

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Authors and Affiliations

  1. College of Chemistry and Environmental Science, Henan Normal University, Xinxiang, Henan, 453007, China

    Xiangming Han & Yulu Wang

  2. Department of Chemistry and Environmental Engineering, Pingyuan University, Xinxiang, Henan, 453003, China

    Xiangming Han & Huiqiang Ma

Authors
  1. Xiangming Han
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  2. Huiqiang Ma
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  3. Yulu Wang
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Corresponding author

Correspondence to Yulu Wang.

Additional information

Published in Russian in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 6, pp. 872–874.

The text was submitted by the authors in English.

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Han, X., Ma, H. & Wang, Y. A simple and efficient synthesis of 2-aryl-substituted benzimidazoles. Russ J Org Chem 44, 863–865 (2008). https://doi.org/10.1134/S1070428008060146

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  • DOI: https://doi.org/10.1134/S1070428008060146

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