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Three-component synthesis of 2-(4-amino-2,5-dihydro-1H-imidazol-5-ylidene)malononitriles

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Abstract

2-(4-Amino-2,5-dihydro-1H-imidazol-4-ylidene)malononitriles were synthesized by three-component reaction of tetracyanoethylene, carbonyl compound, and ammonium acetate. The synthesis can be performed in two steps with intermediate isolation of 2-aminoethene-1,1,2-tricarbonitrile, as well as using preliminarily prepard 2-aminoethene-1,1,2-tricarbonitrile and 1,3,5-trisubstituted 2,4-diazapentadienes.

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Authors and Affiliations

  1. I.N. Ul’yanov Chuvash State University, Moskovskii pr. 15, Cheboksary, 428015, Russia

    O. V. Ershov, A. V. Eremkin, Ya. S. Kayukov, A. N. Lyshchikov & O. E. Nasakin

  2. Faculty of Chemistry, Moscow State University, Vorob’evy gory 1, Moscow, 119992, Russia

    V. A. Tafeenko

Authors
  1. O. V. Ershov
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  2. A. V. Eremkin
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  3. Ya. S. Kayukov
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  4. A. N. Lyshchikov
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  5. O. E. Nasakin
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  6. V. A. Tafeenko
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Corresponding author

Correspondence to O. V. Ershov.

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Original Russian Text © O.V. Ershov, A.V. Eremkin, Ya.S. Kayukov, A.N. Lyshchikov, O.E. Nasakin, V.A. Tafeenko, 2008, published in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 4, pp. 575–581.

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Ershov, O.V., Eremkin, A.V., Kayukov, Y.S. et al. Three-component synthesis of 2-(4-amino-2,5-dihydro-1H-imidazol-5-ylidene)malononitriles. Russ J Org Chem 44, 570–576 (2008). https://doi.org/10.1134/S1070428008040179

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  • DOI: https://doi.org/10.1134/S1070428008040179

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