Abstract
2-Nitro- and 2-amino-4,5-difluoroanilines were used as starting materials to synthesize fluorine-containing imidazole, oxazole, and indoloquinoxaline derivatives. The latter may be regarded as ellipticine analogs.
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References
Fluorine-Containing Molecules. Structure, Reactivity, Synthesis, and Applications, Liebman, J.F., Greenberg, A., and Dolbier, W.R., Jr., Eds., New York: VCH, 1988.
Organofluorine Compounds in Medicinal Chemistry and Biomedical Applications, Filler, R., Kobayashi, Y., and Yagupolski, L.M., Eds., Amsterdam: Elsevier, 1993.
Nosova, E.V., Mochul’skaya, N.N., Kotovskaya, S.K., Lipunova, G.N., and Charushin, V.N., Heteroatom Chem., 2006, vol. 17, p. 579.
Kotovskaya, S.K., Romanova, S.A., Charushin, V.N., Chupakhin, O.N., and Kodess, M.I., J. Fluorine Chem., 2004, vol. 125, p. 421.
Kotovskaya, S.K., Charushin, V.N., Perova, N.M., Kodess, M.I., and Chupakhin, O.N., Synth. Commun., 2004, vol. 34, p. 137.
Kotovskaya, S.K., Baskakova, Z.M., Charushin, V.N., Chupaquin, O.N., Belanov, E.F., Bormotov, N.I., Balakhnin, S.M., and Serova, O.A., Khim.-Farm. Zh., 2005, no. 11, p. 12.
Suffness, M. and Cordell, C.A., The Alkaloids, 1985, vol. 25, p. 89.
Gribble, G.W., The Alkaloids, 1990, vol. 39, p. 239.
Ishikura, M., Hino, A., Yaginuma, T., Aata, I., and Katagiri, N., Tetrahedron, 2000, vol. 56, p. 193.
Chabane, H., Lamazzi, C., Thiery, V., Guilaumet, G., and Besson, T., Tetrahedron Lett., 2002, vol. 43, p. 2483.
Krayushkin, M.M., Yarovenko, V.N., and Zavarzin, I.V., Izv. Ross. Akad. Nauk, Ser. Khim., 2004, p. 491.
Zavarzin, I.V., Yarovenko, V.N., Shirokov, A.V., Smirnova, N.G., Es’kov, A.A., and Krauyshkin, M.M., Arkivoc, 2003, part (xiii), p. 205.
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Dedicated to Full Member of the Russian Academy of Sciences V.A. Tartakovskii on the 75th anniversary of his birth
Original Russian Text © V.N. Yarovenko, A.V. Polushina, K.S. Levchenko, I.V. Zavarzin, M.M. Krayushkin, S.K. Kotovskaya, V.N. Charushin, 2007, published in Zhurnal Organicheskoi Khimii, 2007, Vol. 43, No. 9, pp. 1391–1396.
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Yarovenko, V.N., Polushina, A.V., Levchenko, K.S. et al. Synthesis of fluorine-containing analogs of ellipticine and other heterocycles from 2-Nitro-and 2-amino-4,5-difluoroanilines. Russ J Org Chem 43, 1387–1392 (2007). https://doi.org/10.1134/S1070428007090217
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DOI: https://doi.org/10.1134/S1070428007090217