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Some modern methods for estimation of reactivity of organic compounds

Russian Journal of Organic Chemistry volume 43, pages 483–500 (2007)Cite this article

Abstract

The review analyzes main tendencies in the development of some modern methods for estimation of reactivity of organic compounds and reaction regioselectivity. The up-to-date correlation analysis, reactivity descriptors, QSPR, and other methods are compared with respect to their advantages and disadvantages.

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Authors and Affiliations

  1. St. Petersburg State Institute of Technology, Moskovskii pr. 26, St. Petersburg, 190013, Russia

    Yu. E. Zevatskii & D. V. Samoilov

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  1. Yu. E. Zevatskii
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  2. D. V. Samoilov
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Original Russian Text © Yu.E. Zevatskii, D.V. Samoilov, 2007, published in Zhurnal Organicheskoi Khimii, 2007, Vol. 43, No. 4, pp. 487–504.

Yurii Zevatskii was born in 1969 in Kiev. In 1993 he graduated from the Department of Chemical Technology of Organic Dyes and Phototropic Compounds, St. Petersburg State Institute of Technology. Candidate of chemical sciences since 2005. Yu. Zevatskii is now head of the Research Laboratory at Novbytkhim Ltd.

Field of scientific interest: physical organic chemistry.

Denis Samoilov was born in 1974 in Leningrad. In 1997 he graduated from the Department of Chemical Technology of Organic Dyes and Phototropic Compounds, St. Petersburg State Institute of Technology. Candidate of chemical sciences since 2001. D. Samoilov is now Senior research worker at the Physical Chemistry Department, St. Petersburg State Institute of Technology.

Fields of scientific interest: physical organic chemistry and chemistry of xanthene dyes.

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Zevatskii, Y.E., Samoilov, D.V. Some modern methods for estimation of reactivity of organic compounds. Russ J Org Chem 43, 483–500 (2007). https://doi.org/10.1134/S107042800704001X

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  • DOI: https://doi.org/10.1134/S107042800704001X

Keywords

  • Substituent Effect
  • Reactivity Index
  • Fukui Function
  • Local Softness
  • Local Hardness