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Synthesis of pyrroloisoquinolines from papaverine

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Abstract

papaverine and its derivatives react with p-chlorophenacyl bromide to give the corresponding quaternary salts, which are converted into pyrrolo[2,1-a]isoquinolines by the action of bases.

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Authors and Affiliations

  1. St. Petersburg State Institute of Technology, Moskovskii pr. 26, St. Petersburg, 190013, Russia

    D. V. Krivorotov, M. V. Vorob’ev & E. N. Glibin

  2. Vekton Ltd., St. Petersburg, Russia

    V. A. Polukeev

Authors
  1. D. V. Krivorotov
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  2. M. V. Vorob’ev
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  3. V. A. Polukeev
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  4. E. N. Glibin
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Additional information

Original Russian Text © D.V. Krivorotov, M.V. Vorob’ev, V.A. Polukeev, E.N. Glibiu. 2006, published in Zhurnal Organicheskoi Khimii, 2006, Vol. 42. No. 4, pp. 594–596.

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Krivorotov, D.V., Vorob’ev, M.V., Polukeev, V.A. et al. Synthesis of pyrroloisoquinolines from papaverine. Russ J Org Chem 42, 577–579 (2006). https://doi.org/10.1134/S1070428006040154

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  • DOI: https://doi.org/10.1134/S1070428006040154

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