Russian Journal of Organic Chemistry

, Volume 42, Issue 3, pp 365–368

Synthesis of chiral 5-aryltetrahydrofuran-2-ones via yeast bioreduction of γ-keto acids and their esters

  • N. O. Mahmoodi
  • R. Yousefi-Malekroudi

DOI: 10.1134/S1070428006030043

Cite this article as:
Mahmoodi, N.O. & Yousefi-Malekroudi, R. Russ J Org Chem (2006) 42: 365. doi:10.1134/S1070428006030043


Enantioselective reduction of γ-keto acids and related γ-keto esters with Saccharomyces cerevisiae (baker’s yeast) leads to the formation of the corresponding chiral 5-aryltetrahydrofuran-2-ones in satisfactory chemical and optical yields.

Copyright information

© Pleiades Publishing, Inc. 2006

Authors and Affiliations

  • N. O. Mahmoodi
    • 1
  • R. Yousefi-Malekroudi
    • 1
  1. 1.Organic Research LaboratoryDepartment of Chemistry University of GuilanRashtIran

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