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Synthesis of New Bis(arylsulfanyl Diketones) as Promising Building Blocks with Fungicidal Activity

  • Organic Synthesis and Industrial Organic Chemistry
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Russian Journal of Applied Chemistry Aims and scope Submit manuscript

An Erratum to this article was published on 01 June 2023

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Abstract

A procedure was developed for preparing block synthons by the reaction of 2,4-pentanedione, 1,2-ethanedithiol, and aromatic aldehydes in the presence of an organic catalyst (triethylamine, piperidine, diazabicycloundecene, morpholine) to construct heterocycles derived from bis(arylmethylsulfanyl diketones). Among the bis(sulfanyl diketones) prepared, the compounds containing p-methoxyphenyl and thienyl substituents in the methinesulfanyl moiety showed the highest fungicidal activity toward phytopathogenic fungi Bipolaris sorokiniana, Fusarium oxysporum, and Rhizoctonia solani.

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Funding

The interdisciplinary study was performed in accordance with the research plan of the Institute of Petroleum Chemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences (FMRS-2022-0074 and FMRS-2022-0079) and within the framework of the government assignment of the Ministry of Science and Higher Education of the Russian Federation no. 075032021607, theme no. 122031100163-4, using the equipment of the Agidel Center for Shared Use, Ufa Federal Research Center, Russian Academy of Sciences.

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Authors and Affiliations

  1. Institute of Petroleum Chemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, 450075, Bashkortostan, Russia

    N. S. Akhmadiev & V. R. Akhmetova

  2. Ufa Institute of Biology, Ufa Federal Research Center, Russian Academy of Sciences, Ufa, 450054, Bashkortostan, Russia

    N. F. Galimzyanova

Authors
  1. N. S. Akhmadiev
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  2. N. F. Galimzyanova
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  3. V. R. Akhmetova
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Contributions

N.S. Akhmadiev: experiments on synthesis, isolation, and identification of the desired bis(arylsulfanyl diketones); N.F. Galimzyanova: experiments on primary screening of the compounds synthesized for fungicidal activity; V.R. Akhmetova: task setting and discussion of the results.

Corresponding author

Correspondence to V. R. Akhmetova.

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The authors declare that they have no conflicts of interest.

Additional information

Translated from Zhurnal Prikladnoi Khimii, No. 5, pp. 528–536, August, 2023 https://doi.org/10.31857/S0044461823050029

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Akhmadiev, N.S., Galimzyanova, N.F. & Akhmetova, V.R. Synthesis of New Bis(arylsulfanyl Diketones) as Promising Building Blocks with Fungicidal Activity. Russ J Appl Chem 96, 594–601 (2023). https://doi.org/10.1134/S1070427223050129

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  • DOI: https://doi.org/10.1134/S1070427223050129

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