Abstract
The objective of the current work is to evaluate the selective extraction of zinc(II) from copper(II) ions from their binary system as a simulated mode for separation of 64,67Cu from irradiation Zn target using a variety of extractants diluted in kerosene from chloride medium. The different factors affecting the extraction system such as extraction time, hydrochloric acid, hydrogen ions, extractant type, extractant concentrations, chloride ions and temperature were studied in order to obtain the best conditions for the extraction process. Trioctylphosphine oxide (TOPO) is efficient and promising for selective extraction of Zn over Cu from HCl by high extraction % (91.32%) within 10 min, the extracted zinc(II) species was suggested to be HZnCl3·2TOPO while copper was almost completely not extracted. Stripping was successfully accomplished by 0.01 M NaCl solution, and 5 min was sufficient to strip the loaded Zn(II) ions completely. The extraction and striping operations took around 25 min to complete separation of Zn(II)/Cu(II) from the binary system. The negative values of ΔH and ΔS variation indicate the exothermic behavior of the extraction process. As a result, TOPO is a promising extractant with a high efficiency for extracting zinc from copper and the potential for reuse for eleven cycles nearly with the same efficiency. Therefore, the sequences involved in fast separation with high purity between Zn(II)/ Cu(II) in the binary system using TOPO as extractant can be recommended to separate 64,67Cu as a theranostic radionuclide from irradiated Zn target.
REFERENCES
Sarangi, K. and Das, R.P., Hydrometallurgy, 2004, vol. 71, pp. 335–342. https://doi.org/10.1016/S0304-386X(03)00085-9
Xin, B., Jiang, W., Aslam, H., Zhang, K., Liu, C., Wang, R., and Wang, Y., Bioresour. Technol., 2012, vol. 106, p. 147. https://doi.org/10.1016/j.biortech.2011.12.013
Beata, P., Sep. Sci. Technol., 2014, vol. 49, no. 11, pp. 1706–1712. https://doi.org/10.1080/01496395.2014.906456
Hoogerstraete, T.V., Onghena, B., and Binnemans, K., Int. J. Mol. Sci., 2013, vol. 14, pp. 21353–21377.
Lee, L.Y., Morad, N., Ismail, N., Talebi, A., and Rafatullah, M., Int. J. Mol. Sci., 2020, vol. 21, p. 6860. https://doi.org/10.3390/ijms21186860
Regel, M., Sastre, A.M., and Szymanawski, J., Environ. Sci. Technol., 2001, vol. 35, pp. 630–635. https://doi.org/10.1021/es001470w
Reddy, D.R. and Priya, D.N., Sep. Purif. Technol., 2005, vol. 45, pp. 163–167. https://doi.org/10.1016/j.seppur.2005.02.014
Lerum, H., Sand, S., Eriksen, D., and Wibetoe, G., J. Radioanal. Nucl. Chem., 2020, vol., 324 no. 3, pp. 1–12. https://doi.org/10.1007/s10967-020-07168-8
Zhu, Z., Zhang, W., and Cheng, C.Y., Hydrometallurgy, 2012, vol. 113-114, pp. 155–159. https://doi.org/10.1016/j.hydromet.2011.12.016
Saha, S., Fundamentals of Nuclear Pharmacy, 3rd ed., Springer- Verlag, New York, Inc., 1992. https://doi.org/10.1007/978-1-4757-4027-1_8
Blower, P.J., Jason, J.S., and Zweit, J., Nucl. Med. Biol., 1996, vol. 23, p. 957. https://doi.org/10.1016/s0969-8051(96)00130-8
Takeda, A., Tamano, H., Enomoto, S., and Oku, N., Exp. Mol. Pathol., 2003, vol. 8, pp. 216–224.
Yeye, Z., Li, J., Xu, X., Man, Z., Bin, Z., Shengming, D., and Wu, Y., Technol. Cancer Res. Treat., 2019, vol. 18, pp. 1–10. https://doi.org/10.1177/1533033819830758
Merrick, M.J., Rotsch, D.A., Tiwari, A., Nolen, J., Brossard, T., Song, J., Wadas, T.J., Sunderland, J.J., and Graves, S.A., Med. Biol., 2021, vol. 66, p. 035002
Smith, N.A., Bowers, D.L., and Ehst, D.A., A Review. Appl. Radiat. Isotopes, 2012, vol. 70, pp. 2377–2383.
Ikotun, O.F. and Lapi, S.E., Future Med. Chem., 2011, vol. 3, pp. 599–621.
Asabella, A.N., Cascini, G.L., Altini, C., Paparella, D., Notaristefano, A., and Rubini, G., Bio. Med. Res. Intl., 2014, vol. 2014, pp. 1–9.
Vyas, C.K., Park, J.H., and Yang, S.D., J. Radiopharm. Mol. Probes., 2016, vol. 2, no. 2, pp. 84–95.
Pupillo, G., Mou, L., Martini, P., Pasquali, M., Boschi, A., Cicoria, G., Duatti, A., Haddad, F., and Esposito, J., Radiochim. Acta, 2020, vol. 108, no. 8, pp. 593–602. https://doi.org/10.1515/ract-2019-3199
Mou, L., Martini, P., Pupillo, G., Cieszykowska, I., Cutler, C.S., and Mikołajczak, R., A Mini. Review. Molecules, 2022, vol. 27, p. 1501. https://doi.org/10.3390/molecules27051501
Smith, S.V., Waters, D.J., and Bartolo, N.D., Radiochim. Acta, 1996, vol. 75, pp. 65–68.
Rowshanfarzad, P., Jalilian, A. R., and Sabet, M., Nucleonika, 2005, vol. 50, no. 3, pp. 97–103
Gyrarkey, F. and Sato, C.S., Exp. Mol. Pathol., 1968, vol. 8, pp. 216–224.
Tamhina, B., Herak, M.J., and Jagodic, V., Croactica Chemica Acata CCACAA, 1973, vol. 45(4), pp. 593–601.
Xie, Q., Zhu, H., Wang, F., Meng, X., Ren, Q., Xia, C., and Yang, Z., Molecules, 2017, vol. 22, p. 641. https://doi.org/10.3390/molecules22040641
Zimmerann, H. K., Schaub, E., Hirzel, W., Schubiger, P.A., and Schibli, R., Q J. Nicl. Med. Mol. Imaging, 2008, vol. 52, pp. 145–150
Dasgupta, K., Mausner, L.F., and Srivastava, S.C., Appl. Radial. Isot., 1991, vol. 42, no. 4, pp. 371-376.
Kim, J.H., Park, H., and Chun, K.S., Appl. Radial. Isot., 2010, vol. 68, pp. 1623–1626.
Pedersen, K.S., Nielsen, K.M., Fonslet, J., Jensen, M., and Zhuravlev, F., Solv. Extr. Ion Exch., 2019, vol. 37, no. 5, pp. 376–391. https://doi.org/10.1080/07366299.2019.1646982
Mishra, S. and Devi, N., Hydrometallurgy, 2011, vol. 107, pp. 29–33. https://doi.org/10.1016/j.hydromet.2010.12.016.
El Dessouky, S.I., El-Nadi, Y.A., Ahmed, I.M., Saad, E.A., and Daoud, J.A., Chem. Engineer. Process, 2008, vol. 47, pp. 177–183. https://doi.org/10.1016/j.cep.2007.03.002
Lum, K.H., Stevens, G.W., and Kentish, S.E., Hydrometallurgy, 2014, vol. 142, pp. 108–115. https://doi.org/10.1016/j.hydromet.2013.11.016
Tian, M., Mu, F., Jia, Q., Quan, X., and Liao, W., J. Chem. Eng. Data, 2011, vol. 56, p. 2225. https://doi.org/10.1021/je101245d
Vinício, F.I., Júlio, C.A., Rubens, S., da Silvab, S., Cláudio, A.V., and José, L.M., Química Nova, 2018, vol. 41, pp. 770–777. https://doi.org/10.21577/0100-4042.20170249
Hu, J., Chen, Q., Yang, X., Hu, F., Hu, H., and Yin, Z., Sep. Purif. Technol., 2012, vol. 87, pp. 15–21. https://doi.org/10.1016/j.seppur.2011.11.006
Willy, K., Stoyan, G., Jean, F., David, B., and Ilunga, N., Sep. Purif. Technol., 2010, vol. 45, pp. 535–540. https://doi.org/10.1080/01496390903529869
Laso, J., García, V., Bringas, E., Urtiaga, A.M., and Ortiz, I., I. Ind. Eng. Chem. Res., 2015, vol. 54, pp. 3218−3224. https://doi.org/10.1021/acs.iecr.5b00099
Cierpiszewski, R. and Szymanowski, J., Solv. Extr. Ion Exch., 2001, vol. 19, no. 3, pp. 441–456. https://doi.org/10.1081/SEI-100103279
Rogers, D.W., Concise Physical Chemistry, New York: John Wiley & Sons, 2001.
Sinha, M.K., Sahu, S.K., Meshram, P., Pandey, B.D., and Kumar, V., Int. J. Mater. Metall. Eng., 2001, vol. 1, no. 2, pp. 28–34. https://doi.org/10.5923/j.ijmee.20120102.04
Obaseki, O.O., Ipinmoroti, K.O., and Ajayi, O.O., Glob. J. Pure Appl. Sci., 2006, vol. 12, no. 1, pp. 93–97. https://doi.org/10.4314/gjpas.v12i1.16573
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Rizk, H.E., Imam, D.M. & Attallah, M.F. Potential Fast and Promising Separation for Valuable Ions of Biomedical Interest. Russ J Appl Chem 96, 385–394 (2023). https://doi.org/10.1134/S1070427223030163
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DOI: https://doi.org/10.1134/S1070427223030163