Abstract
Nitration of α-, β-, and γ-cyclodextrins with nitric acid of various concentrations was studied. The nitration occurs similarly for all the three cyclodextrins studied. The influence of the reaction conditions on the degree of substitution of hydroxy groups in cyclodextrin by nitrate groups was examined. The composition and degree of substitution of the nitration products depend not only on the nitric acid concentration, but also on the molar ratio of HNO3 to OH groups. The results obtained allow optimization of the procedure for preparing cyclodextrin nitrates with definite topology of substitution of cyclodextrin hydroxy groups.
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References
Del Valle, E.M.M., Process Biochem., 2004, vol. 39, no. 9, pp. 1033–1046.
Cahill, S., Rinzler, A.G., Owens, F.J., and Bulusu, S., J. Phys. Chem., 1994, vol. 98, no. 28, pp. 7095–7100.
Crini, G., Chem. Rev., 2014, vol. 114, no. 21, pp. 10940–10975.
Patent US5114506, Publ. 1992.
Patent US6293201,. Publ. 2001.
Patent US6468370, Publ. 2002.
Karyakin, Yu.V. and Angelov, I.I., Chistye khimicheskie veshchestva (Pure Chemicals), Moscow: Khimiya, 1974, 4th ed.
Romanova, L.B., Barinova, L.S., Lagodzinskaya, G.V., Kazakov, A.I., and Mikhailov, Yu.M., Russ. J. Appl. Chem., 2014, vol. 87, no. 12, pp. 1884–1889.
Eremenko, L.T., Moiseeva, E.I., and Kustova, L.V., Russ. Chem. Bull., 1967, vol. 15, no. 8, pp. 1292–1295.
Eremenko, L.T. and Korolev, A.M., Russ. Chem. Bull., 1967, vol. 15, no. 8, pp. 1375–1377.
Rogovin, Z.A., Khimiya tsellyulozy (Cellulose Chemistry), Moscow: Khimiya, 1972.
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Original Russian Text © Yu.M. Mikhailov, L.B. Romanova, A.E. Tarasov, M.A. Rakhimova, A.V. Darovskikh, L.S. Barinova, 2018, published in Zhurnal Prikladnoi Khimii, 2018, Vol. 91, No. 7, pp. 1049−1054.
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Mikhailov, Y.M., Romanova, L.B., Tarasov, A.E. et al. Preparation of Cyclodextrin Nitrates. Russ J Appl Chem 91, 1217–1221 (2018). https://doi.org/10.1134/S1070427218070224
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DOI: https://doi.org/10.1134/S1070427218070224