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Synthesis of D,L-Lactide–ε-Caprolactone Copolymers and Preparation of Films Based on Them

  • Macromolecular Compounds and Polymeric Materials
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Abstract

D,L-Lactide–ε-caprolactone copolymers were synthesized by polymerization in the bulk. Films of these copolymers were prepared, and their strain properties and degradation rate under physiological conditions were studied. Introduction of ε-caprolactone into the copolymer increases the film elasticity and decreases the degradation rate compared to poly(D,L-lactide) homopolymer, and also favors spreading of human keratinocytes. The films obtained can be used for treatment of wounds and burns.

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Authors and Affiliations

  1. Institute of Cytology, Russian Academy of Sciences, St. Petersburg, Russia

    Yu. A. Nashchekina, D. M. Darvish & M. I. Blinova

  2. Ioffe Institute, ul. Politekhnicheskaya 26, St. Petersburg, 194021, Russia

    Yu. A. Nashchekina

  3. Institute of Chemistry, St. Petersburg State University, St. Petersburg, Russia

    K. E. Kurdyukova, I. M. Zorin & A. Yu. Bilibin

  4. Peter the Great Polytechnic University, ul. Politekhnicheskaya 29, St. Petersburg, 195251, Russia

    E. S. Tsobkallo

Authors
  1. Yu. A. Nashchekina
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  2. K. E. Kurdyukova
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  3. I. M. Zorin
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  4. D. M. Darvish
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  5. E. S. Tsobkallo
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  6. M. I. Blinova
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  7. A. Yu. Bilibin
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Corresponding author

Correspondence to Yu. A. Nashchekina.

Additional information

Original Russian Text © Yu.A. Nashchekina, K.E. Kurdyukova, I.M. Zorin, D.M. Darvish, E.S. Tsobkallo, M.I. Blinova, A.Yu. Bilibin, 2018, published in Zhurnal Prikladnoi Khimii, 2018, Vol. 91, No. 1, pp. 123−130.

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Nashchekina, Y.A., Kurdyukova, K.E., Zorin, I.M. et al. Synthesis of D,L-Lactide–ε-Caprolactone Copolymers and Preparation of Films Based on Them. Russ J Appl Chem 91, 113–120 (2018). https://doi.org/10.1134/S1070427218010184

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  • DOI: https://doi.org/10.1134/S1070427218010184

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