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Synthesis and properties of polymeric and organo-inorganic amphiphilic sorbents molecularly imprinted with cholesterol

  • Sorption and Ion Exchange Processes
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Abstract

Polymeric and organo-inorganic sorbents molecularly imprinted with cholesterol were synthesized to create selective hemosorbents for efferent therapy of hypercholesterlemia. These sorbents are block copolymers of 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate and granulated organo-inorganic sorbents in which the imprinting was performed in the layer of the above copolymer on the surface of selenium (Se) nanoparticles stabilized with polyvinyl pyrrolidone. The physicochemical and sorption properties of the sorbents were studied.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, Bol’shoi pr. 31, St. Petersburg, 199004, Russia

    I. V. Polyakova, L. N. Borovikova, N. M. Ezhova, O. A. Pisarev, E. N. Vlasova & B. Z. Volchek

  2. Department of Medical Physics, Peter the Great St. Petersburg Polytechnic University, ul. Politekhnicheskaya 29, St. Petersburg, 195251, Russia

    A. A. Osipenko & O. A. Pisarev

Authors
  1. I. V. Polyakova
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  2. A. A. Osipenko
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  3. L. N. Borovikova
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  4. N. M. Ezhova
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  5. O. A. Pisarev
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  6. E. N. Vlasova
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  7. B. Z. Volchek
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Correspondence to I. V. Polyakova.

Additional information

Original Russian Text © I.V. Polyakova, A.A. Osipenko, L.N. Borovikova, N.M. Ezhova, O.A. Pisarev, E.N. Vlasova, B.Z. Volcheka, 2015, published in Zhurnal Prikladnoi Khimii, 2015, Vol. 88, No. 10, pp. 1432-1442.

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Polyakova, I.V., Osipenko, A.A., Borovikova, L.N. et al. Synthesis and properties of polymeric and organo-inorganic amphiphilic sorbents molecularly imprinted with cholesterol. Russ J Appl Chem 88, 1617–1626 (2015). https://doi.org/10.1134/S1070427215100109

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  • DOI: https://doi.org/10.1134/S1070427215100109

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