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Thermodynamic properties of biologically active substances: 3-acetyl-9-methoxy-2-phenyl-11H-indolizino[8,7-b]indole and 8-acetylharmine

  • Physicochemical Studies of Systems and Processes
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Abstract

The enthalpies of solution of 3-acetyl-9-methoxy-2-phenyl-11H-indolizino[8,7-b]indole and 8-acetylharmine in dimethyl sulfoxide were measured by isothermal calorimetry at solute: solvent molar ratios of 1: 9000, 1: 18000, and 1: 36000. From the data obtained, the standard enthalpies of solution of the compounds in dimethyl sulfoxide at infinite dilution were calculated. The heat capacities of 8-acetylharmine were determined by dynamic calorimetry in the interval 298.15–673 K, and the C op = f(T) equations were obtained. The standard enthalpies of combustion of the compounds were estimated by approximate methods, and their heats of melting were calculated. From the data obtained, using Hess cycle, the standard enthalpies of formation of the compounds were calculated.

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Authors and Affiliations

  1. Abishev Chemical-Metallurgical Institute, Karaganda, Kazakhstan

    Sh. B. Kasenova, A. Zh. Abil’daeva & B. K. Kasenov

  2. Fitokhimiya International Research and Production Holding, Joint-Stock Company, Karaganda, Kazakhstan

    Zh. S. Nurmaganbetov & S. M. Adekenov

Authors
  1. Sh. B. Kasenova
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  2. A. Zh. Abil’daeva
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  3. B. K. Kasenov
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  4. Zh. S. Nurmaganbetov
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  5. S. M. Adekenov
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Correspondence to Sh. B. Kasenova.

Additional information

Original Russian Text © Sh.B. Kasenova, A.Zh. Abil’daeva, B.K. Kasenov, Zh.S. Nurmaganbetov, S.M. Adekenov, 2012, published in Zhurnal Prikladnoi Khimii, 2012, Vol. 85, No. 12, pp. 2029–2033.

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Kasenova, S.B., Abil’daeva, A.Z., Kasenov, B.K. et al. Thermodynamic properties of biologically active substances: 3-acetyl-9-methoxy-2-phenyl-11H-indolizino[8,7-b]indole and 8-acetylharmine. Russ J Appl Chem 85, 1914–1918 (2012). https://doi.org/10.1134/S1070427212120208

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  • DOI: https://doi.org/10.1134/S1070427212120208

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