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Thermodynamic and kinetic aspects of a single-reactor synthesis of 5-amino-3-methyl-1,2,4-triazole hydrochloride from aminoguanidine and acetic acid

  • Organic Synthesis and Industrial Organic Chemistry
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Abstract

Fundamental thermodynamic and kinetic aspects of the reaction in which acetic acid guanyl hydrazide is formed from aminoguanidine and acetic acid in aqueous solutions at pH 0.6-1.5 and the kinetics of cyclization of acetic acid guanyl hydrazide hydrochloride to 5-amino-3-methyl-1,2,4-triazole hydrochloride in a melt were studied. Methods for synthesis of acetic acid guanyl hydrazide hydrochlorides and 5-amino-3-methyl-1,2,4-triazole hydrochloride were developed.

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Authors and Affiliations

  1. South-Russian State Technical University (Novocherkassk Polytechnic Institute), Novocherkassk, Rostov-on-Don oblast, Russia

    E. V. Tarasova, V. M. Chernyshev, A. V. Chernysheva & R. S. Abagyan

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  1. E. V. Tarasova
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  2. V. M. Chernyshev
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  3. A. V. Chernysheva
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  4. R. S. Abagyan
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Additional information

Original Russian Text © E.V. Tarasova, V.M. Chernyshev, A.V. Chernysheva, R.S. Abagyan, 2011, published in Zhurnal Prikladnoi Khimii, 2011, Vol. 84, No. 3, pp. 408–414.

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Tarasova, E.V., Chernyshev, V.M., Chernysheva, A.V. et al. Thermodynamic and kinetic aspects of a single-reactor synthesis of 5-amino-3-methyl-1,2,4-triazole hydrochloride from aminoguanidine and acetic acid. Russ J Appl Chem 84, 400–406 (2011). https://doi.org/10.1134/S1070427211030116

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  • DOI: https://doi.org/10.1134/S1070427211030116

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