Skip to main content
Log in

Monolithic methacrylate polymeric sorbents: Development of methods for chemical modification of the surface for the subsequent bioaffine functionalization

  • Macromolecular Chemistry and Polymeric Materials
  • Published:
Russian Journal of Applied Chemistry Aims and scope Submit manuscript


Copolymers containing aldehyde, succinimidyl carbonate, and imidazolecarbamate groups were prepared by polymer-analogous transformations of epoxy groups of a macroporous monolithic polymeric support derived from glycidyl methacrylate and ethylene glycol dimethacyrlate. The effect of certain parameters on the course of the copolymer modification and immobilization of a protein on the surface of the polymeric support was studied. The possibility of using the matrices obtained for development of biorecognizing systems was examined.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others


  1. Tennikova, T.B., Bleha, M., Svec, F., et al., J. Chromatogr., 1991, vol. 555, pp. 97–107.

    Article  CAS  Google Scholar 

  2. Tennikova, T.B. and Svec, F., J. Chromatogr., 1993, vol. 646, pp. 279–288.

    Article  CAS  Google Scholar 

  3. Ostryanina, N.D., Il’ina, O.V., and Tennikova, T.B., J. Chromatogr. B, 2002, vol. 770, pp. 35–43.

    Article  CAS  Google Scholar 

  4. Svec, F. and Frechet, J.M.J., Monolithic Materials: Preparation, Properties and Applications, Svec, F., Tennikova, T.B., and Deyl, Z., Eds., Amsterdam: Elsevier, 2003, pp. 19–50.

    Google Scholar 

  5. Vlakh, E. and Tennikova, T., J. Sep. Sci., 2007, vol. 30, pp. 2801–2813.

    Article  CAS  Google Scholar 

  6. Meringova, L.F., Leont’eva, G.F., Gupalova, T.V., et al., Biotekhnologiya, 2000, vol. 4, pp. 45–53.

    Google Scholar 

  7. Khimich, G.N., Rakhmatullina E.N., Slabospitskaya, M.Yu., and Tennikova, T.B., Zh. Prikl. Khim., 2005, vol. 78, no. 4, pp. 623–628.

    CAS  Google Scholar 

  8. Dechant, J., Danz, R., Kimmer, W., et al., Ultrarotspektroskopische Untersuchungen an Polymeren, Berlin: Akademie, 1972.

    Google Scholar 

  9. Shriner, R.L., Fuson, R.C., Curtin, D.Y., and Morrill, T.C., The Systematic Identification of Organic Compounds. A Laboratory Manual, New York: Wiley, 1980, 6th ed.

    Google Scholar 

  10. Dawson, R.M.C., Elliot, D.C., Elliot, W.H., and Jones, K.M., Data for Biochemical Research, Oxford: Clarendon, 1986.

    Google Scholar 

  11. Slabospitskaya, M.Yu., Vlakh, E.G., Razdol’skaya, N.V., et al., in Sbornik trudov konferentsii “Izmeritel’nye i informatsionnye tekhnologii v okhrane zdorov’ya “Metromed-2007”” (Proc. Conf. “Measurement and Information Technologies in Health Protection “Metromed-2007””), St. Petersburg, April 17–19, 2007, pp. 191–196.

Download references

Author information

Authors and Affiliations


Additional information

Original Russian Text © E.S. Sinitsyna, E.N. Vlasova, E.G. Vlakh, T.B. Tennikova, 2008, published in Zhurnal Prikladnoi Khimii, 2008, Vol. 81, No. 8, pp. 1326–1332.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sinitsyna, E.S., Vlasova, E.N., Vlakh, E.G. et al. Monolithic methacrylate polymeric sorbents: Development of methods for chemical modification of the surface for the subsequent bioaffine functionalization. Russ J Appl Chem 81, 1403–1409 (2008).

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: