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The use of monolithic polymeric sorbents to simulate virus-cell interactions

  • Macromolecular Chemistry and Polymeric Materials
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Abstract

A simple virus-cell complementary model system can be obtained using polymer-analogous reactions of the epoxy groups of glycidyl methacrylate-ethylene glycol dimethacrylate monolithic macroporous polymeric support and of the carboxy groups of styrene-methyl methacrylate polymeric nanospheres. The effect of thus designed microenvironment on the affinity binding parameters of virus-mimicking nanoparticles with the functionalized sorbent surface is studied by high-performance monolithic disk affinity chromatography.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia

    I. V. Kalashnikova, N. D. Ivanova & T. B. Tennikova

Authors
  1. I. V. Kalashnikova
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  2. N. D. Ivanova
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  3. T. B. Tennikova
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Additional information

Original Russian Text © I. V. Kalashnikova, N.D. Ivanovo, T.B. Tennikova, 2008, published in Zhurnal Prikladnoi Khimii, 2008, Vol. 81, No. 5, pp. 830–836.

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Kalashnikova, I.V., Ivanova, N.D. & Tennikova, T.B. The use of monolithic polymeric sorbents to simulate virus-cell interactions. Russ J Appl Chem 81, 867–873 (2008). https://doi.org/10.1134/S1070427208050285

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  • DOI: https://doi.org/10.1134/S1070427208050285

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