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Synthesis of Novel Tetrahydropyrimidines via the Reaction of Sodium [1-(3,3-Diethoxypropyl)ureido]methanesulfonates with C-Nucleophiles

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Abstract

A series of new substituted tetrahydropyrimidines was obtained by the reaction of sodium [1-(3,3-diethoxypropyl)ureido]methanesulfonates with various C-nucleophiles (4-chlororesorcinol, sesamol, 2,4-dihydroxybenzoic acid, 4-hydroxy-6-methyl-2H-pyran-2-one) in chloroform in the presence of trifluoroacetic acid.

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ACKNOWLEDGMENTS

The authors are grateful to the Spectro-Analytical Center of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences” for the technical support.

Funding

This work financially supported by Council for Grants of the President of the Russian Federation for young Russian scientists—candidates of sciences (grant no. MK-1944.2022.1.3).

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Authors and Affiliations

  1. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”, 420088, Kazan, Russia

    A. V. Smolobochkin, T. S. Rizbayeva, A. S. Gazizov, A. R. Burilov & M. A. Pudovik

  2. Kazan National Research Technological University, 420015, Kazan, Russia

    L. J. Yakhshilikova

Authors
  1. A. V. Smolobochkin
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  2. L. J. Yakhshilikova
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  3. T. S. Rizbayeva
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  4. A. S. Gazizov
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  5. A. R. Burilov
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  6. M. A. Pudovik
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Corresponding author

Correspondence to A. V. Smolobochkin.

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A.R. Burilov is a member of the editorial board of the Russian Journal of General Chemistry. The other authors declare no conflicts of interest.

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Smolobochkin, A.V., Yakhshilikova, L.J., Rizbayeva, T.S. et al. Synthesis of Novel Tetrahydropyrimidines via the Reaction of Sodium [1-(3,3-Diethoxypropyl)ureido]methanesulfonates with C-Nucleophiles. Russ J Gen Chem 93, 495–499 (2023). https://doi.org/10.1134/S1070363223030052

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