Skip to main content
SpringerLink
Log in

Synthesis, Crystal Structure, and Activity of Cu(II) and Zn(II) Complexes of 2-Mercaptoquinoline N-Oxide

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

The mononuclear Cu(II) complex, Zn(II) complex, and homodinuclear Zn(II)-Zn(II) complex of 2-mercaptoquinoline N-oxide, have been synthesized as possible antibacterial agents. Their crystal structures analyzed by X-ray diffraction methods have shown that the structures of the two mononuclear complexes and a homodinuclear complex are markedly different. The antibacterial activities of complexes were investigated using the Oxford Cup method, and the result indicated that complexes have good antibacterial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme
Fig. 1.

REFERENCES

  1. Zalevskaya, O.A. and Gur’eva, Y.A., Russ. J. Coord. Chem., 2021, vol. 47, p. 861. https://doi.org/10.1134/S1070328421120046

  2. Salcedo-Sora, J.E., Robison, A.T.R., Zaengle-Barone, J., Franz, K.J., and Kell, D.B., Molecules, 2021, vol. 26, p. 5826. https://doi.org/10.3390/molecules26195826

  3. Paek, S.M., Jo, W.Y., Park, M., and Choy, J.H., J. Nanosci. Nanotechno., 2007, vol. 7, p. 3867. https://doi.org/10.1166/jnn.2007.060

  4. Mangion, S.E., Holmes, A.M., and Roberts, M.S., Int. J. Mol. Sci., 2021, vol. 22, p. 9730. https://doi.org/10.3390/ijms22189730

  5. Turley, P.A., Fenn, R.J., and Ritter, J.C., Biofouling, 2000, vol. 15, p. 175. https://doi.org/10.1080/08927010009386308

  6. Niu, L.J., Xin, Q.U., Everaert, E., Center, S.T., Ingredients, A.S., Center, E.T., and Ingredients, A.S., China Surfactant Detergent & Cosmetics, 2016, vol. 46, p. 709. https://doi.org/10.13218/j.cnki.csdc.2016.12.007

  7. Neeta, K., Sambit, N.B., Shukla, D., Shyama, D., Taru, S., Manjeet, J., and Ashwini, K.A., ACS Appl. Mater. Interfaces, 2021, vol. 13, p. 47382. https://doi.org/10.1021/acsami.1c14113

    Article  CAS  Google Scholar 

  8. Piérard-Franchimont, C., Goffin, V., Decroix, J., and Piérard, G.E., Skin Pharmacol. Appl. Skin Physiol., 2002, vol. 15, p. 434. https://doi.org/10.1159/000066452

  9. Reeder, N.L., Xu, J., Youngquist, R.S., Schwartz, J.R., Grant, R.A., and Saunders, C.W., Brit. J. Dermatol., 2011, vol. 165, p. 9. https://doi.org/10.1111/j.1365-2133.2011.10571.x

  10. Feng, J., Chen, J., Chen, M.J., Su, X.L., and Shi, Q.S., J. Appl. Polym. Sci., 2017, vol. 134, p. 45148. https://doi.org/10.1002/app.45148

  11. Song, B., Cao, N.T., Zhang, J., and Xie, J.W., Mol. Catal., 2021, vol. 516. https://doi.org/10.1016/j.mcat.2021.111981

  12. Wang,Y.S., Yang, S.J., Ahmad, M.J., Ding, Z.M., Duan, Z.Q., Chen, Y.W., Liu, M., Liang, A.X., Hua, G.H., and Huo, L.J., Ecotox. Environ. Safe., 2022, vol. 234, p. 113393. https://doi.org/10.1016/j.ecoenv.2022.113393

  13. Zhang, J.A., Zhang, L.J., Zou, X.Z., Liu, Y.J., Gao, W., and Li, Y., Inorg. Chem. Commun., 2016, vol. 64, p. 7. https://doi.org/10.1016/j.inoche.2015.11.017

  14. Chi, H.Y., Shi, J.M., Li, H.N., Wei, W., Cottrill, E., Pan, N., Chen, H., Liang,Y., Yu, L., Zhang, Y.Q., and Hou, C., Dalton Trans., 2013, vol. 42, p. 15559. https://doi.org/10.1039/C3DT51476E

  15. Yu, L., Shi, J.M., Zhang, Y.Q., Wang, Y.Q., Fan, Y.N., Zhang, G.Q., Shi, W., and Cheng, P., J. Mol. Struct., 2011, vol. 987, p. 138. https://doi.org/10.1016/j.molstruc.2010.11.074

  16. Dolomanov, O.V., Bourhis, L.J., Gildea, R.J., Howard, J.A.K., and Puschmann, H., J. Appl. Crystallogr., 2009, vol. 42, p. 339. https://doi.org/10.1107/S0021889808042726

  17. Furia, T.E. and Steinberg, D.H., US Patent 3961054, 1976.

  18. Shen, S.M., Appendino, G., and Guo, Y.W., Nat. Prod. Rep., 2022, vol. 39, p. 1803. https://doi.org/10.1039/D2NP00023G

  19. Zhang, Y., Wu, Y.T., Zheng, W., Han, X.X., Jiang, Y.H., Hu, P.L., Tang, Z.X., and Shi, L.E., J. Funct. Foods, 2017, vol. 38, p. 273. https://doi.org/10.1016/j.jff.2017.09.047

  20. Chavez-Esquivel, G., Cervantes-Cuevas, H., Ybieta-Olvera, L.F., Briones, M.T.C., Acosta, D., and Cabello, J., Mater. Sci. Eng. C., 2021, vol. 123. https://doi.org/10.1016/j.msec.2021.111934

Download references

Funding

This was financially supported by the National Natural Science Foundation of China Youth Fund Program (52103042), Jiangsu Subei Science and Technology Special Program (SZ-LYG202017), Jiangsu Postgraduate Research and Practice Innovation Program (KYCX2021-042), Jiangsu Undergraduate Innovation and Entrepreneurship Program (SY202211641637013).

Author information

Authors and Affiliations

  1. School of Environment and Chemical Engineering, Jiangsu Ocean University, 222005, Lianyungang, China

    J. Ji, C. Liu, Y. Chen & Z. Zhang

  2. School of Pharmacy, Jiangsu Ocean University, 222005, Lianyungang, China

    H. Li

  3. School of Polymer Science and Engineering, Sichuan University, 610065, Chengdu, China

    R. Li

Authors
  1. J. Ji
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. C. Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Y. Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. R. Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Z. Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Z. Zhang.

Ethics declarations

No conflict of interest was declared by the authors.

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ji, J., Li, H., Liu, C. et al. Synthesis, Crystal Structure, and Activity of Cu(II) and Zn(II) Complexes of 2-Mercaptoquinoline N-Oxide. Russ J Gen Chem 93, 182–188 (2023). https://doi.org/10.1134/S1070363223010243

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363223010243

Keywords:

Search

Navigation