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Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety

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Abstract

A novel series of poly-heterocyclic compounds containing quinoline as antiviral agents against HIV have been designed and synthesized. Structures of these novel derivatives have been confirmed by IR, NMR, and EI-MS spectra. Most of the products have been tested for their HIV inhibitory activity and characterized by high to moderate activity.

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ACKNOWLEDGMENTS

The authors extend their appreciation to the Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia for funding this research work through the project number (IF- PSAU-2021/01/19030).

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Authors and Affiliations

  1. Preparatory Year Deanship, Basic Science Department, Prince Sattam Bin Abdulaziz University, 11942, Alkharj, Saudi Arabia

    Farag A. El-Essawy

  2. Chemistry Department, Faculty of Science, Menoufia University, 32511, Shebin El-Koam, Egypt

    Farag A. El-Essawy & Nader M. Boshta

  3. Department of Chemistry, College of Science, Mashreq University, 53113, Mashreq, Sudan

    Noora T. G. Ali

  4. Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, 13317, Bonn, Germany

    Nader M. Boshta

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  1. Farag A. El-Essawy
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  2. Noora T. G. Ali
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  3. Nader M. Boshta
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Correspondence to Farag A. El-Essawy.

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El-Essawy, F.A., Ali, N.T.G. & Boshta, N.M. Synthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety. Russ J Gen Chem 92, 1129–1136 (2022). https://doi.org/10.1134/S1070363222060263

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  • DOI: https://doi.org/10.1134/S1070363222060263

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