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Reactions of N-Benzyl- and N-(2-Phenylethyl)maleimides with Secondary Amines

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Abstract

It was found that the reactions of N-benzylmaleimide with secondary amines proceed at the double C=C bond and lead to the formation of 3-N,N-R2-aminosubstituted succinimides. In the case of N-phenethylmaleimide, the nucleophilic addition of secondary amines is accompanied by an amidation reaction, which proceeds with ring opening and leads to the formation of unsymmetrical maleic acid diamides.

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Authors and Affiliations

  1. I.N. Ulyanov Chuvash State University, 428015, Cheboksary, Russia

    O. A. Kolyamshin, V. A. Danilov & Yu. Yu. Pylchikova

  2. I.Ya. Yakovlev Chuvash State Pedagogical University, 428000, Cheboksary, Russia

    Yu. N. Mitrasov & A. A. Avruyskaya

Authors
  1. O. A. Kolyamshin
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  2. Yu. N. Mitrasov
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  3. V. A. Danilov
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  4. A. A. Avruyskaya
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  5. Yu. Yu. Pylchikova
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Correspondence to O. A. Kolyamshin.

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Kolyamshin, O.A., Mitrasov, Y.N., Danilov, V.A. et al. Reactions of N-Benzyl- and N-(2-Phenylethyl)maleimides with Secondary Amines. Russ J Gen Chem 92, 745–749 (2022). https://doi.org/10.1134/S1070363222050012

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  • DOI: https://doi.org/10.1134/S1070363222050012

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