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Role of Water in the Photochemical Synthesis of Methyl 12-Oxo-6,12-dihydroazepino[2,1-b]quinazoline-8-carboxylates

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Abstract

Methyl 12-oxo-6,12-dihydroazepino[2,1-b]quinazoline-8-carboxylate and methyl 3H-azepin-2(1H)-one-5-carboxylate were synthesized by photoinduced heterocyclization of methyl 4-azidobenzoate and ethyl 2-aminobenzoate in the THF–water and acetonitrile­–water mixtures. It was found that the yields of methyl 12-oxo-6,12-dihydroazepino[2,1-b]quinazolate increase with rising water content in the reaction mixture.

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Authors and Affiliations

  1. National Research Lobachevsky State University of Nizhny Novgorod, 603950, Nizhny Novgorod, Russia

    A. V. Budruev, M. A. Giricheva, D. A. Davydov, A. V. Pokrovskaia & A. L. Pronina

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  1. A. V. Budruev
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  2. M. A. Giricheva
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  3. D. A. Davydov
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  4. A. V. Pokrovskaia
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  5. A. L. Pronina
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Correspondence to A. V. Budruev.

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Translated from Zhurnal Obshchei Khimii, 2021, Vol. 91, No. 8, pp. 1171–1176 https://doi.org/10.31857/S0044460X21080047.

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Budruev, A.V., Giricheva, M.A., Davydov, D.A. et al. Role of Water in the Photochemical Synthesis of Methyl 12-Oxo-6,12-dihydroazepino[2,1-b]quinazoline-8-carboxylates. Russ J Gen Chem 91, 1448–1452 (2021). https://doi.org/10.1134/S1070363221080041

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  • DOI: https://doi.org/10.1134/S1070363221080041

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