Abstract
A procedure has been developed for the synthesis of 6,7-dihydroindazoles and 7,8-dihydroquinazolines by reaction of 3,4-dihydroxanthone derivatives with 1,2- and 1,3-binucleophiles (hydrazine, guanidine). The reaction occurred under mild conditions (methanol, 20-65°C) with high yields.
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Funding
This study was performed under partial financial support by the Council for Grants at the President of the Russian Federation (project no. SP-2019) and in the framework of state assignment of the Ministry of Health of the Russian Federation (project no. AAAA-A20-120121790030-8).
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Translated from Zhurnal Obshchei Khimii, 2021, Vol. 91, No. 7, pp. 1036–1041 https://doi.org/10.31857/S0044460X21070076.
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Chernov, N.M., Lebedev, M.Y., Luk’yanenko, V.I. et al. Synthesis of 6,7-Dihydroindazole and 7,8-Dihydroquinazoline Derivatives from Ethyl 4,4-Dimethyl-9-oxo-3,4-dihydro-9H-xanthene-2-carboxylates. Russ J Gen Chem 91, 1305–1309 (2021). https://doi.org/10.1134/S1070363221070070
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DOI: https://doi.org/10.1134/S1070363221070070