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1-Allyl- and 1-(2-Bromopropyl)-2-amino-3-carboxy(carbalkoxy)methylbenzimidazolium Quaternary Salts in the Synthesis of Imidazo[1,2-a]benzimidazole Derivatives

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Abstract

1-Allyl(2-bromopropyl)-3-carboxy(carbalkoxy)methyl-2-aminobenzimidazolium halides and their 2-iminobenzimidazoline forms were synthesized. Their cyclization into functionalized imidazo[1,2-a]benzimidazole derivatives was studied. Some further transformations of obtained imidazobenzimidazoles with the participation of reactive substituents and an activated methylene group were studied.

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ACKNOWLEDGMENTS

This work was carried out using the equipment of the Center for Collective Use of the Southern Federal University.

Funding

This work was financially supported by the Ministry of Science and Higher Education of the Russian Federation (State assignment in the field of scientific activity, Southern Federal University, 2020, project FENW-2020-0031 (0852-2020-0031)).

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Authors and Affiliations

  1. Research Institute of Physical and Organic Chemistry, Southern Federal University, 344090, Rostov-on-Don, Russia

    O. N. Zhukovskaya, A. S. Morkovnik & G. S. Borodkin

Authors
  1. O. N. Zhukovskaya
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  2. A. S. Morkovnik
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  3. G. S. Borodkin
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Corresponding author

Correspondence to A. S. Morkovnik.

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No conflict of interest was declared by the authors.

Additional information

Translated from Zhurnal Obshchei Khimii, 2021, Vol. 91, No. 7, pp. 998–1009 https://doi.org/10.31857/S0044460X21070039.

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Zhukovskaya, O.N., Morkovnik, A.S. & Borodkin, G.S. 1-Allyl- and 1-(2-Bromopropyl)-2-amino-3-carboxy(carbalkoxy)methylbenzimidazolium Quaternary Salts in the Synthesis of Imidazo[1,2-a]benzimidazole Derivatives. Russ J Gen Chem 91, 1271–1281 (2021). https://doi.org/10.1134/S1070363221070033

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