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Synthesis of 4-Aryl-6-oxo-5-cyano-1,6-dihydropyridine-2-carboxylic Acids and Their Methyl Esters by Reacting Methyl Acylpyruvates with Malononitrile and Cyanoacetamide

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Abstract

A series of new methyl 4-aryl-6-oxo-5-cyano-1,6-dihydropyridine-2-carboxylates and 4-aryl-6-oxo-5-cyano-1,6-dihydropyridine-2-carboxylic acids were synthesized by reacting methyl esters of acylpyruvic acids with malononitrile and cyanoacetamide, respectively.

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Authors and Affiliations

  1. Ulyanov Chuvash State University, 428015, Cheboksary, Russia

    M. A. Maryasov, N. P. Romashov, V. V. Davydova, O. E. Nasakin & M. P. Osipova

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  1. M. A. Maryasov
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  2. N. P. Romashov
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  3. V. V. Davydova
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  4. O. E. Nasakin
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  5. M. P. Osipova
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Correspondence to M. A. Maryasov.

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Translated from Zhurnal Obshchei Khimii, 2021, Vol. 91, No. 5, pp. 816–820 https://doi.org/10.31857/S0044460X2105019X.

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Maryasov, M.A., Romashov, N.P., Davydova, V.V. et al. Synthesis of 4-Aryl-6-oxo-5-cyano-1,6-dihydropyridine-2-carboxylic Acids and Their Methyl Esters by Reacting Methyl Acylpyruvates with Malononitrile and Cyanoacetamide. Russ J Gen Chem 91, 947–950 (2021). https://doi.org/10.1134/S1070363221050261

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