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Synthesis of 2-Aryl-5-oxo-5H-thiopyrano[4,3-b]pyridine-7-carboxylic Acids as the First Representatives of a New Heterocyclic System

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Abstract

A series of ethyl 2-[(Z)-(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-6-arylnicotinoates was obtained as a result of the reaction of 6-aryl-2-formylnicotinoates with rhodanine. Under alkaline conditions, they underwent recyclization to form 2-aryl-5-oxo-5H-thiopyrano[4,3-b]pyridine-7-carboxylic acids—the first representatives of new heterocyclic system.

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Authors and Affiliations

  1. Danylo Halytsky Lviv National Medical University, 79010, Lviv, Ukraine

    T. I. Chaban

  2. Ivan Franko National University of Lviv, 79005, Lviv, Ukraine

    V. S. Matiychuk

Authors
  1. T. I. Chaban
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  2. V. S. Matiychuk
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Correspondence to T. I. Chaban.

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Chaban, T.I., Matiychuk, V.S. Synthesis of 2-Aryl-5-oxo-5H-thiopyrano[4,3-b]pyridine-7-carboxylic Acids as the First Representatives of a New Heterocyclic System. Russ J Gen Chem 90, 1578–1580 (2020). https://doi.org/10.1134/S1070363220080290

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  • DOI: https://doi.org/10.1134/S1070363220080290

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