Skip to main content
Log in

Tetravalent Platinum Complexes: Synthesis, Structure, and Antimicrobial Activity

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

The complexes [(C2H5)2NH2]2[PtCl6], [(C2H5)4N]2[PtCl6], and [(CH3)3NH]2[PtCl6] were prepared by the reaction of hexachloroplatinic acid with organylammonium chlorides in acetonitrile. Structure of these compounds was determined by X-ray analysis and infrared spectroscopy. The synthesized crystals consist of tetrahedral organylammonium cations and hexachloroplatinate octahedral anions. The antimicrobial activity of the synthesized complexes against the Escherichia coli strain M-17 was studied.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1.
Fig. 2.

Similar content being viewed by others

REFERENCES

  1. Almodares, Z., Lucas, S.J., Basri, A.M., Pask, C.M., Hebden, A.J., Phillips, R.M., and McGowan, P.C., Inorg. Chem., 2014, vol. 53, no. 2, p. 72. https://doi.org/10.1021/ic401529u

    Article  CAS  Google Scholar 

  2. Farrell, N., Chem. Soc. Rev., 2015, vol. 44, no. 24, p. 8773. https://doi.org/10.1039/C5CS00201J

    Article  PubMed  CAS  Google Scholar 

  3. Kukushkin, V.Yu. and Pan’kov, E.Yu., Zh. Obshch. Khim., 1987, vol. 57, no. 10, p. 2691.

    Google Scholar 

  4. Yam, V.W.W., Chan, K.H.Y., and Wong, K.M.C., Chem. Eur. J., 2015, vol. 11., no. 15, p. 4535. https://doi.org/10.1002/chem.200500106

    Article  Google Scholar 

  5. Wheate, N.J. and Collins, J.G., Coord. Chem. Rev., 2004, vol. 241, p. 133. https://doi.org/10.1016/S0010-8545(03)00050-X

    Article  CAS  Google Scholar 

  6. Verlee, A, Mincke, S., and Stevens, C.V., Carbohydr. Polym., 2017, vol. 164, p. 268. https://doi.org/10.1016/j.carbpol.2017.02.001

    Article  PubMed  CAS  Google Scholar 

  7. Elshabrawy, R.F.M., Refaee, A.A., and El-Sawi, E.A., Carbohydr. Polym., 2016, vol. 146, p. 376.

    Article  CAS  Google Scholar 

  8. Raman, N., Selvan, A., and Sudharsan, S., Spectrochim. Acta, 2011, vol. 79, p. 873. https://doi.org/10.1016/j.saa.2011.03.017.V

    Article  CAS  Google Scholar 

  9. Sankarganesh, M., Dhaveethu, Raja J., Sakthikumar, K., Solomon, R.V., Rajesh, J., Athimoolam, S., and Vijayakumar, V., Bioorg. Chem., 2018, vol. 81, p. 144. https://doi.org/10.1016/j.bioorg.2018.08.006

    Article  PubMed  CAS  Google Scholar 

  10. Lunagariya, M.V., Thakor, K.P., Varma, R.R., Waghela, B.N., Pathak, C., and Patel, M.N., Med. Chem. Commun., 2017, vol. 9, no. 2, p. 282. https://doi.org/10.1039/c7md00472a

    Article  CAS  Google Scholar 

  11. Kohl, H.H., Haghighi, S., and McAuliffe, C.A., Chem. Biol. Interact., 1980, vol. 29, no. 3, p. 327. https://doi.org/10.1016/0009-2797(80)90151-9

    Article  PubMed  CAS  Google Scholar 

  12. Vartanyan, A.A. and Ogorodnikova, M.V., Ross. Bioterapevt. Zh., 2004, no. 1, p. 14.

    Google Scholar 

  13. Galea, A.M. and Murray, V., Biochim. Biophys. Acta, 2002, vol. 1579, p. 142. https://doi.org/10.1016/s0167-4781(02)00535-3

    Article  PubMed  CAS  Google Scholar 

  14. Gelasco, A. and Lippard, S.J., Biochem., 1998, vol. 37, p. 9230. https://doi.org/10.1021/bi973176v

    Article  CAS  Google Scholar 

  15. Peshikova, M.V., Dolgushin, I.I., and Rusanova, N.N., Zh. Mikrobiol., Epidemiol. Immunobiol., 2002, no. 1, p. 70.

    Google Scholar 

  16. Dmitrieva, N.V., Petukhova, I.N., and Smolyanskaya, A.Z., Prakt. Onkol., 2001, vol. 2, no. 1(5), p. 18.

    Google Scholar 

  17. Pravosudova, N.A. and Mel’nikov, V.L., Nauchnyi Al’manakh, 2015, vols. 10–13, no. 12, p. 351. https://doi.org/10.17117/na.2015.10.03.351

    Article  Google Scholar 

  18. Shishkova, Yu.S., Darovskikh, S.N., Vil’danova, O.P., and Babikova, M.S., Ross. Immunol. Zh., 2017, vol. 11, no. 20, no. 3, p. 574.

    Google Scholar 

  19. Debabov, D.V., Biotekhnol., 2012, no. 4, p. 7.

    Google Scholar 

  20. Kovalishena, O.V., Altbashina, L.A., and Saperkin, N.V., Zh. Medial’., 2014, no. 3, no. 13, p. 72.

    Google Scholar 

  21. Petruzzella, E., Sirota, R., Solazzo, I., Gandin, V., and Gibson, D., Chem. Sci., 2018, vol. 9, p. 4299.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Sharutin, V.V., Sharutina, O.K., Senchurin, V.S., and Tkacheva, A.R., Russ. J. Gen. Chem., 2018, vol. 88, no. 7, p. 1456. https://doi.org/10.1134/S1070363218070174

    Article  CAS  Google Scholar 

  23. Tkacheva, A.R., Sharutin, V.V., and Sharutina, О.K., Russ. J. Gen. Chem., 2019, vol. 89, no. 2, p. 277. https://doi.org/10.1134/S107036321902018X

    Article  CAS  Google Scholar 

  24. Galanski, M. and Keppler, B.K., Anti-Cancer Agents Med. Chem., 2007, vol. 7, p. 55. https://doi.org/10.2174/187152007779314017

    Article  CAS  Google Scholar 

  25. Brown, J.M., Methods Enzym., 2007, vol. 435, p. 297. https://doi.org/10.1016/S0076-6879(07)35015-5

    Article  CAS  Google Scholar 

  26. Wheate, N.J., Walker, S., Craig, G.E., and Oun, R., Dalton Trans., 2010, vol. 39, p. 8113. https://doi.org/10.1039/C0DT00292E

    Article  PubMed  CAS  Google Scholar 

  27. Tkacheva, A.R., Vestn. YuUrGU, Ser. Khim., 2017, vol. 9, no. 4, p. 74. https://doi.org/10.14529/chem170412

    Article  Google Scholar 

  28. Tkacheva, A.R., Sharutin, V.V., Sharutina, О.K., and Slepukhin, P.A., Russ. J. Gen. Chem., 2019, vol. 89, no. 9, p. 1816. https://doi.org/10.1134/S1070363219090147

    Article  CAS  Google Scholar 

  29. Shlepotina, N.M., Kolesnikov, O.L., Shishkova, O.S., Galagudin, I.V., Tkacheva, A.R., and Sharutin, V.V., Ross. Immunol. Zh., 2019, vol. 13, no. 22, no. 2, p. 1063.

    Google Scholar 

  30. Bruker. SMART and SAINT-Plus. Versions 5.0. Data Collection and Processing Software for the SMART System. Bruker AXS Inc., 1998, Madison, Wisconsin, USA.

  31. Bruker. SHELXTL/PC. Versions 5.10. An Integrated System for Solving, Refining and Displaying Crystal Structures from Diffraction Data. Bruker AXS Inc., 1998, Madison, Wisconsin, USA.

  32. Dolomanov, O.V., Bourhis, L.J., Gildea, R.J., Howard, J.A.K., and Puschmann, H., J. Appl. Cryst., 2009, vol. 42, p. 339. https://doi.org/10.1107/S0021889808042726

    Article  CAS  Google Scholar 

Download references

Funding

The work was carried out with the financial support of the Ministry of Education and Science of the Russian Federation (grant no. 4.6151.2017/8.9).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. R. Tkacheva.

Ethics declarations

No conflict of interest was declared by the authors.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tkacheva, A.R., Sharutin, V.V., Sharutina, O.K. et al. Tetravalent Platinum Complexes: Synthesis, Structure, and Antimicrobial Activity. Russ J Gen Chem 90, 655–659 (2020). https://doi.org/10.1134/S1070363220040155

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363220040155

Keywords:

Navigation