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Functionalization of 2-Phosphoryl-Substituted Phenols

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Abstract

The nitration, bromination, diazo coupling, sulfonation, and alkylation of the aromatic ring of a series of 2-phosphoryl-substituted phenols have been studied for the first time. 2,6-Diphosphorylphenols have been obtained for the first time via 1,3-phosphorotropic phosphate-phosphonate rearrangement. The alkylation of 2-(diphenylphosphoryl)phenol at the hydroxy group with 2-bromo- and 2-chloroethanols has been studied under conventional heating and microwave irradiation conditions.

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Funding

This study was performed under partial financial support by the Russian Foundation for Basic Research (project no. 19-03-00262) in the framework of state assignment for the Institute of Physiologically Active Compounds of the Russian Academy of Sciences.

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Authors and Affiliations

  1. Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow oblast, Russia

    Yu. I. Rogacheva & V. E. Baulin

  2. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russia

    D. V. Baulin, V. E. Baulin & A. Yu. Tsivadze

Authors
  1. Yu. I. Rogacheva
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  2. D. V. Baulin
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  3. V. E. Baulin
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  4. A. Yu. Tsivadze
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Corresponding author

Correspondence to D. V. Baulin.

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Conflict of Interests

No conflict of interest was declared by the authors.

Russian Text © The Author(s), 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 8, pp. 1206–1215.

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Rogacheva, Y.I., Baulin, D.V., Baulin, V.E. et al. Functionalization of 2-Phosphoryl-Substituted Phenols. Russ J Gen Chem 89, 1595–1603 (2019). https://doi.org/10.1134/S1070363219080097

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  • DOI: https://doi.org/10.1134/S1070363219080097

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