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Synthesis of 2N-Alkyl-substituted 5-Amino-3-imino-1,2,4-thiadiazolines

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Abstract

Conditions for an efficient and a readily reproducible synthesis of a series of 2N-Alkyl-substituted 5-amino-3-imino-1,2,4-thiadiazolines by the direct alkylation of 3,5-diamino-1,2,4-thiadiazole with alkyl bromides in fairly high yields (up to 76%).

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Authors and Affiliations

  1. Research Institute of Macroheterocyclic Chemistry, Ivanovo State University of Chemistry and Technology, Sheremetevskii pr. 7, Ivanovo, 153000, Russia

    Yu. V. Butina, T. V. Kudayarova & E. A. Danilova

Authors
  1. Yu. V. Butina
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  2. T. V. Kudayarova
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  3. E. A. Danilova
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Correspondence to E. A. Danilova.

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Original Russian Text © Yu.V. Butina, T.V. Kudayarova, E.A. Danilova, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 6, pp. 939–942.

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Butina, Y.V., Kudayarova, T.V. & Danilova, E.A. Synthesis of 2N-Alkyl-substituted 5-Amino-3-imino-1,2,4-thiadiazolines. Russ J Gen Chem 88, 1120–1123 (2018). https://doi.org/10.1134/S1070363218060129

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  • DOI: https://doi.org/10.1134/S1070363218060129

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