Abstract
4-Substituted 3-arylhydrazono-2,4-dioxobutanoates acids esters undergo cyclization under the action of hydrazine hydrate to form 4-arylazo-3-pyrazolecarboxylic acids derivatives. The structure of the compounds obtained was determined from spectral methods.
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References
Ivanskii, V.I., Khimiya geterotsiklicheskikh sodinenii (Chemistry of Heterocyclic Compounds), Moscow: Visshaya Shkola, 1978.
Perevalov, S.G., Burgart, Ya.V., Saloutin, V.I., and Chupakhin, O.N., Russ. Chem. Rev., 2001, vol. 70, no. 11, p. 921. doi 10.1070/RC2001v070n11ABEH000685
Milyutin, A.V., Makhmudov, R.R., Andreichikov, Yu.S., Goleneva, A.F., Tulbovich, G.A., and Kovina, T.I., Pharm. Chem. J., 1996, vol. 30, no. 6, p. 374. doi 10.1007/BF02219323
Geffken, D., Soliman, R., Soliman, F., Abdel-Khalen Magdi, M., and Issa, D., Med. Chem. Res., 2011, vol. 20, no. 4, p. 408. doi 10.1007/s00044-010-9328-z
Pimenova, E.V. and Voronina, E.V., Pharm. Chem. J., 2001, vol. 35, no. 11, p. 602. doi 10.1023/A:1015141710100.
RU Patent 2198165, 2003.
Levenets, T.V., Koz’minykh, V.O., and Tolstikova, A.O., Vestn. YuUGU, 2012, vol. 9, no. 24(283), p.32.
Levenets, T.V., Koz’minykh, V.O., and Tolstikova, A.O., J. Struct. Chem., 2013, vol. 54, no. 1, p. 186. doi 10.1134/S0022476613010290
Levenets, T.V., Koz’minykh, V.O., and Koz’minykh, E.N., Izv. Vuzov, Ser. Khim. i Khim. Tekhnol., 2013, vol. 56, no. 2, p.22.
Pretch, E., Bühlmann, P., and Affolter, C., Structure Determination of Organic Compounds: Tables of Spectral Data, Berlin: Springer, 2000.
Fokin, A.S., Burgart, Ya.V., and Saloutin, V.I., Russ. J. Org. Chem., 2006, vol. 42, no. 6, p. 887. doi 10.1134/S1070428006060133
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Original Russian Text © T.V. Levenets, V.O. Koz’minykh, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 6, pp. 909–913.
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Levenets, T.V., Koz’minykh, V.O. Reactions of 3-Arylhydrazono-2,4-dioxobutanoates with Hydrazine Hydrate. Russ J Gen Chem 88, 1090–1094 (2018). https://doi.org/10.1134/S1070363218060075
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DOI: https://doi.org/10.1134/S1070363218060075