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Synthesis and Properties of Functional Derivatives of 2,6-Diisobornylphenol and 2-Isobornyl-6-(1-phenylethyl)phenol

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Abstract

New isobornylphenol derivatives have been produced by introducing allyl, hydroxypropyl, and chloropropyl groups into the para-position of 2,6-diisobornylphenol and 2-isobornyl-6-(1-phenylethyl)phenol. The radical scavenging and antioxidant activity and the membrane-protective properties of the newly-obtained compounds in chemical and biological model systems were studied.

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Acknowledgments

The work was done with financial support from the Russian Foundation for Basic Research (project no. 16- 33-00338). This work was performed using the equipment of the “Chemistry” Center for Collective Use at the Institute of Chemistry (Komi Scientific Centre, Ural Branch, Russian Academy of Sciences) and the “Molecular Biology” Center for Collective Use at the Institute of Biology (Komi Scientific Centre, Ural Branch, Russian Academy of Sciences). The used animals were obtained from the scientific collection of experimental animals at the Institute of Biology (Komi Scientific Centre, Ural Branch, Russian Academy of Sciences) (http://www.ckprf.ru/usu/471933/).

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Correspondence to I. Yu. Chukicheva.

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Original Russian Text © O.V. Shchukina, I.Yu. Chukicheva, O.G. Shevchenko, T.A. Kolegova, K.Yu. Suponitsky, A.V. Kutchin, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 4, pp. 580–592.

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Shchukina, O.V., Chukicheva, I.Y., Shevchenko, O.G. et al. Synthesis and Properties of Functional Derivatives of 2,6-Diisobornylphenol and 2-Isobornyl-6-(1-phenylethyl)phenol. Russ J Gen Chem 88, 664–675 (2018). https://doi.org/10.1134/S1070363218040096

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  • DOI: https://doi.org/10.1134/S1070363218040096

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