Russian Journal of General Chemistry

, Volume 88, Issue 4, pp 650–657 | Cite as

One-Pot Synthesis of N-Substituted Alkylaminocyclohexanols by the Addition of Electrophiles Formed in situ in the System Н2О2 + HBr (HCl)

  • O. A. Sadygov
  • Kh. M. Alimardanov
  • Sh. I. Ismailova
  • N. R. Babaev


Highly selective one-pot synthesis of N-substituted aminocyclohexanols has been performed by hydroxyhalogenation of the corresponding cyclohexenes with electrophilic reagents formed in situ in the system Н2О2 + HHlg (Hlg = Cl, Br), with subsequent substitution of halogen atoms with amines. Some products were tested as antimicrobial additives to motor oils and cooling lubricants and showed high antibacterial and antifungal activity.


hydroxyhalogenation electrophilic intermediates aminocyclohexanols alicyclic aminoalcohols 


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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • O. A. Sadygov
    • 1
  • Kh. M. Alimardanov
    • 1
  • Sh. I. Ismailova
    • 1
  • N. R. Babaev
    • 1
  1. 1.Mammadaliyev Institute of Petrochemical ProcessesAzerbaijan National Academy of SciencesBakuAzerbaijan

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