Abstract
Radical copolymerization of N-vinylpyrrolidone and 2-aminoethyl methacrylate hydrochloride has been studied. Molecular and hydrodynamic characteristics of the resulting copolymers have been determined, and their structure has been confirmed. Conditions favoring conversion of these copolymers into copolymers of N-vinylpyrrolidone with 2-aminoethyl methacrylate of different composition have been elucidated. The suitability of the prepared copolymers as polymeric carriers of monofluoroquinolone ofloxacin has been demonstrated.
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Original Russian Text © M.V. Solovskii, M.S. Borisenko, A.Yu. Ershov, N.V. Zakharova, E.B. Tarabukina, 2017, published in Zhurnal Obshchei Khimii, 2017, Vol. 87, No. 2, pp. 301–306.
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Solovskii, M.V., Borisenko, M.S., Ershov, A.Y. et al. Synthesis of N-vinylpyrrolidone copolymers with 2-aminoethyl methacrylate as drug carriers. Russ J Gen Chem 87, 276–281 (2017). https://doi.org/10.1134/S1070363217020207
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DOI: https://doi.org/10.1134/S1070363217020207