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Synthesis of some new 5-(1-phenyl-1H-1,2,3-triazol-4-yl)-1H-tetrazoles and evaluation of their antimicrobial activity

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Abstract

a series of new tetrazole derivatives were synthesized by a reaction of triazole oxime with sodium azide catalyzed by copper acetate and isolated with high yield under mild conditions. All synthesized compounds were characterized by IR, NMR, and MS data. Evaluation of antimicrobial activity of the products against Gram-positive and Gram-negative bacterial and antifungal strains has been carried out. Among the compounds 3a, 3c, 3e, and 3f exhibited high antibacterial activity and compounds 3a, 3c, 3e demonstrated high antifungal activity.

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References

  1. Butler, R.N., in Comprehensive Het. Chem. II, Katritzky, A.R., Rees, C.W., and Scriven, E.F.V., Eds., Oxford: Pergamon Press, 1996, vol. 4, p. 621

    CAS  Google Scholar 

  2. Butler, R.N., in Comprehensive Heterocyclic Chemistry II, Katritzky, A.R., and Rees, C.W., Eds., Oxford: Pergamon Press, 1984, vol. 5, p. 791.

    Google Scholar 

  3. Singh, H., Chawla, A.S., Kapoor, V.K., Paul, D., and Malhotra, R.K., Prog. Med. Chem., 1980, vol. 17, p. 151.

    Article  CAS  Google Scholar 

  4. Gaponik, P.N., Voitekhovich, S.V., and Ivashkevich, O. A., Russ. Chem. Rev., 2006, vol. 75, p. 507

    Article  CAS  Google Scholar 

  5. Carlucci, L., Ciani, G., and Proserpio, D.M., Angew. Chem., Int. Ed., 1999, vol. 38, p. 3488.

    Article  CAS  Google Scholar 

  6. Habu, T., Mii, N., Kuge, K., Manto, H., and Takamuki, Y., J. Imaging Sci., 1991, vol. 35, p. 202

    CAS  Google Scholar 

  7. Hiskey, M., Chavez, D.E., Naud, D.L., Son, S.F., Berghout, H.L., and Bome, C.A., Proc. Int. Pyrotech. Semin., 2000, vol. 27, p. 3.

    Google Scholar 

  8. Zablocky, J.A., Miyano, M., Sashidhar, N.R., Panzer-Knodle, S., Nicholson, N., and Feigen, L., J. Med. Chem., 1992, vol. 35, p. 4914.

    Article  Google Scholar 

  9. Itoh, F., Yukishige, K., Wajima, M., Ootsu, K., and Akimoto, H., Chem. Pharm. Bull., 1995, vol. 43, p. 230.

    Article  CAS  Google Scholar 

  10. Ortstein, P.L., Arnold, M.B., Evrard, D., Leander, J.D., Lodge, D., and Shoepp, D.D., Bioorg. Med. Chem. Lett., 1993, vol. 3, p. 43.

    Article  Google Scholar 

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Authors and Affiliations

  1. Green and Medicinal Chemistry Laboratory, Department of Chemistry, Osmania University, Hyderabad, 500007, India

    E. Naresh, K. Bhaskar & G. Linga goud

Authors
  1. E. Naresh
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  2. K. Bhaskar
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  3. G. Linga goud
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Correspondence to E. Naresh.

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The text was submitted by the authors in English.

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Naresh, E., Bhaskar, K. & Linga goud, G. Synthesis of some new 5-(1-phenyl-1H-1,2,3-triazol-4-yl)-1H-tetrazoles and evaluation of their antimicrobial activity. Russ J Gen Chem 86, 2862–2864 (2016). https://doi.org/10.1134/S1070363216120513

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  • DOI: https://doi.org/10.1134/S1070363216120513

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