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Synthesis and structure of amides of 4-aryl(hetaryl)-2-pyrrolidone-3-carboxylic acids

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Abstract

Amides of 4-aryl(hetaryl)-2-pyrrolidone-3-carboxylic acids have been prepared via ammonolysis of the corresponding esters of pyrrolidone carboxylic acids. The products structure has been characterized by means of IR, 1H NMR, 1H–13C HMQC, and HMBC spectroscopy.

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References

  1. Mashkovkii, M.D., Lekarstvennye sredstva (Drugs), Moscow: Novaya Volna, 2012.

    Google Scholar 

  2. Registr lekarstvennykh sredstv Rossii. Entsiklopediya lekarstv (Register of Medicines in Russia. Encyclopedia of Drugs), Moscow: OOO “RLS-2002,” 2002, pp. 620, 885.

  3. Granik, V.G., Lekarstva (farmakologicheskii, biokhimicheskii i khimicheskii aspekty) [Drugs (Pharmacological, Biochemical, and Chemical Aspects)], Moscow: Vuzovskaya Kniga, 2006, pp. 149, 153,360.

    Google Scholar 

  4. Gouliaev, A. and Senning, A., Brain Res. Rev., 1994, vol. 19, p. 180. DOI: 10.1016/0165-0173(94)90011-6.

    Article  CAS  Google Scholar 

  5. USSR Patent 797219, 1979; C. A., 1996, vol. 124, 278178.

  6. WO Patent WO2001005399, 2001; C. A., 2001, vol. 134, 110464.

  7. Ostroglyadov, E.S., Vasil’yeva, O.S., Artemova, O.V., and Berestovitskaya, V.M., Russ. J. Org. Chem., 2007, vol. 43, no. 8, p. 1261. DOI: 10.1134/S1070428007080337.

    Article  CAS  Google Scholar 

  8. Nikonorov, A.A., Ostroglyadov, E.S., Vasil’eva, O.S., and Berestovitskaya, V.M., Russ. J. Gen. Chem., 2010, vol. 80, no. 11, p. 2396. DOI: 10.1134/S1070363210110289.

    Article  CAS  Google Scholar 

  9. Berestovitskaya, V.M., Vasil’eva, O.S., and Ostroglyadov, E.S., 2-Pirrolidon i ego proizvodnye (2-Pyrrolidone and Uts Derivatives), St. Petersburg: Asterion, 2013.

    Google Scholar 

  10. Ostroglyadov, E.S., Vasil’eva, O.S., Aleksandrova, S.M., Pelipko, V.V., Berestovitskaya, V.M., Tyurenkov, I.N., and Bagmetova, V.V., Russ. J. Gen. Chem., 2015, vol. 85, no. 8, p. 1838. DOI: 10.1134/S1070363215080095.

    Article  CAS  Google Scholar 

  11. Kobzareva, V.N., Vasil’eva, O.S., Zobacheva, M.M., and Berestovitskaya, V.M., Russ. J. Org. Chem., 1997, vol. 33, no. 10, p. 1519.

    CAS  Google Scholar 

  12. Pretsch, E., Buhlmann, P., and Affolter, C., Structure Determination of Organic Compounds. Tables of Spectral Data, New York: Springer, 2000.

    Book  Google Scholar 

  13. Perlikowska, R., Piekielna, J., Mazur, M., Koralewski, R., Olczak, J., Rego, J-C., Fichna, J., Modranka, J., Janecki, T., and Janecka, A., Bioorg. Med. Chem., 2014, vol. 22, p. 4803. DOI: 10.1016/j.bmc.2014.06.056.

    Article  CAS  Google Scholar 

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Correspondence to V. M. Berestovitskaya.

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Original Russian Text © N.V. Gorodnicheva, E.S. Ostroglyadov, O.S. Vasileva, V.V. Pelipko, O.V. Konarova, V.M. Berestovitskaya, 2016, published in Zhurnal Obshchei Khimii, 2016, Vol. 86, No. 7, pp. 1141–1146.

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Gorodnicheva, N.V., Ostroglyadov, E.S., Vasileva, O.S. et al. Synthesis and structure of amides of 4-aryl(hetaryl)-2-pyrrolidone-3-carboxylic acids. Russ J Gen Chem 86, 1619–1623 (2016). https://doi.org/10.1134/S1070363216070148

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  • DOI: https://doi.org/10.1134/S1070363216070148

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