Skip to main content
Log in

(4-Arylsulfamoyl)phenylcarbamic acid esters: I. Synthesis and activity against herpes viruses

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

Aiming to modify the biological activity of sulfonamides, a number of alkyl (4-arylsulfamoyl)- phenylcarbamates were prepared in 50–70% yield. Biological screening showed that the target compounds possessed a high activity against herpes viruses as well as a traditional antibiotic one.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Strachunskii, L.S. and Kozlov, S.N., Sovremennaya antimikrobnaya khimioterapiya (Modern Antimicrobial Chemotherapy), Moscow: Borges, 2002.

    Google Scholar 

  2. Uetrecht, J.P. and Trager, W., Drug Metabolism: Chemical and Enzymatic Aspects, New York; London: Informa Healthcare, 2007.

    Book  Google Scholar 

  3. Encyclopedia of Drug Metabolism and Interactions, Lyubimov, A.V., Ed., London: Wiley, 2012. DOI: 10.1002/9780470921920.

  4. Chaganava, N.P., Buyanov, V.N., Ershova, Yu.A., Levina, I.I., Safronova, T.S., and Suvorov, N.N., Khim.-Farm. Zh., 1991, vol. 25, no. 8, p. 41.

    CAS  Google Scholar 

  5. Gautam, B., Johnathan, H., Dawn, D., and Salem, M.M., J. Med. Chem., 2004, vol. 47, no. 7, p. 1823. DOI: 10.1021/jm0304461.

    Article  Google Scholar 

  6. Stranix, B.R., Lavalle, J.-F., Sevigy, G., Yelle, J., Perron, V., LeBerre, N., Herbart, D., and Wu, J., Bioorg. Med. Chem. Lett., 2006, vol. 16, no. 13, p. 3459. DOI: 10.1016/j.bmcl. 2006.04.011.

    Article  CAS  Google Scholar 

  7. Ashkinazi, R.I. and Krutikov, V.I., EP Patent 1136472, 2000.

    Google Scholar 

  8. Mel’nikov, N.N. and Baskakov, Yu.A., Khimiya gerbitsidov i regulyatorov rosta rastenii (Chemistry of Herbicides and Plant Growth Regulators), Moscow: Goskhimizdat, 1962.

    Google Scholar 

  9. Gordon, A.J. and Ford, R.A., Chemist’s Companion, Wiley, 1973.

    Google Scholar 

  10. Gentry, A.G., Lawrence, N., and Lushbaugh, N., J. Clin. Microbiol., 1985, vol. 22, no. 2, p. 199.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to V. I. Krutikov.

Additional information

Original Russian Text © V.I. Krutikov, A.V. Erkin, V.V. Tets, A.A. Shmarov, 2016, published in Zhurnal Obshchei Khimii, 2016, Vol. 86, No. 7, pp. 1088–1094.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Krutikov, V.I., Erkin, A.V., Tets, V.V. et al. (4-Arylsulfamoyl)phenylcarbamic acid esters: I. Synthesis and activity against herpes viruses. Russ J Gen Chem 86, 1567–1573 (2016). https://doi.org/10.1134/S1070363216070069

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363216070069

Keywords

Navigation