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Synthesis of novel 1-benzyl/aryl-4-{[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]methyl}-1H-1,2,3-triazole derivatives and evaluation of their antimicrobial activity

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Abstract

A series of 1-benzyl/aryl-4-{[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]methyl}-1H-1,2,3-triazole derivatives were synthesized via Cu(I) catalyzed reaction between terminal alkyne and substituted aryl or benzyl azides. The synthesized triazoles were characterized by 1H NMR, 13C NMR, IR, and mass spectral techniques. All the synthesized compounds were screened for their antimicrobial activity.

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Authors and Affiliations

  1. Department of Chemistry, Osmania University, Hyderabad, Telangana, 500007, India

    B. J. Reddy, V. P. Reddy, G. L. Goud & Y. J. Rao

  2. Department of Genetics, Osmania University, Hyderabad, Telangana, 500007, India

    Premkumar

  3. Department of Chemistry, University College of Science, Osmania University, Saifabad, Hyderabad, Telangana, 500004, India

    K. Supriya

Authors
  1. B. J. Reddy
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  2. V. P. Reddy
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  3. G. L. Goud
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  4. Y. J. Rao
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  5. Premkumar
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  6. K. Supriya
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Correspondence to V. P. Reddy.

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Reddy, B.J., Reddy, V.P., Goud, G.L. et al. Synthesis of novel 1-benzyl/aryl-4-{[(1-aryl-1H-1,2,3-triazol-4-yl)methoxy]methyl}-1H-1,2,3-triazole derivatives and evaluation of their antimicrobial activity. Russ J Gen Chem 86, 1424–1429 (2016). https://doi.org/10.1134/S107036321606030X

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  • DOI: https://doi.org/10.1134/S107036321606030X

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