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Benzyl alcohol-based synthesis of mono- and bis-dihydropyridines in the presence of Al(HSO4)3, sodium nitrite, and sodium bromide under solvent-free conditions

Abstract

Dihydropyridines were synthesized in good to excellent yields in the presence of NaNO2, Al(HSO4)3, and a catalytic amount of NaBr at room temperature. Low cost, the use of available reagents, simple methodology, and easy work-up procedure make this method attractive for organic synthesis.

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Correspondence to L. Z. Fekri.

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Fekri, L.Z., Nikpassand, M. Benzyl alcohol-based synthesis of mono- and bis-dihydropyridines in the presence of Al(HSO4)3, sodium nitrite, and sodium bromide under solvent-free conditions. Russ J Gen Chem 86, 1412–1418 (2016). https://doi.org/10.1134/S1070363216060281

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  • DOI: https://doi.org/10.1134/S1070363216060281

Keywords

  • solvent free
  • dihydropyridine
  • benzyl alcohol
  • Al (HSO4)3